Hollow‐waveguide‐based nanosecond, near‐infrared pulsed laser ablation of tissue
Hollow‐waveguide‐based nanosecond, near‐infrared pulsed laser ablation of tissue
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DOI：
10.1002/lsm.20210
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发表时间：
2005-08
影响因子：
2.4
通讯作者：
Shunichi Sato;Yi-Wei Shi;Y. Matsuura;M. Miyagi;H. Ashida
中科院分区：
文献类型：
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作者：
Shunichi Sato;Yi-Wei Shi;Y. Matsuura;M. Miyagi;H. Ashida
短脉冲固体激光器作为医疗应用的新型相干光源最近受到了广泛关注，但由于激光诱导击穿的发生，其高能量输出脉冲通过固体石英光纤的稳定传输是困难的。我们以前证明，空心波导可以用来提供纳秒激光脉冲的组织消融。本研究的目的是确定最佳的激光脉冲能量和范围的离焦距离，以获得一个深，锋利的消融通道，在心肌组织与激光脉冲通过空心波导传输。
Short‐pulse solid‐state lasers have recently received much attention as new coherent light sources for medical applications, but steady transmission of their high‐energy output pulses through a solid quartz fiber is difficult because of the onset of laser‐induced breakdown. We previously demonstrated that hollow waveguides could be used to deliver nanosecond laser pulses for tissue ablation. The aim of this study was to determine the optimum laser pulse energy and range of defocused distance for obtaining a deep and sharp ablation channel in myocardial tissue with laser pulses transmitted through a hollow waveguide.