Automated Talairach Atlas labels for functional brain mapping
Automated Talairach Atlas labels for functional brain mapping
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DOI：
10.1002/1097-0193(200007)10:3
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发表时间：
2000-07
影响因子：
4.8
通讯作者：
J. Lancaster;M. Woldorff;L. Parsons;M. Liotti;C. Freitas;L. Rainey;P. Kochunov;D. Nickerson;S. Mikiten;P. Fox
中科院分区：
文献类型：
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作者：
J. Lancaster;M. Woldorff;L. Parsons;M. Liotti;C. Freitas;L. Rainey;P. Kochunov;D. Nickerson;S. Mikiten;P. Fox
从1988年的Talairach图谱中检索大脑标签的基于坐标的自动系统，称为Talairach Daemon(TD)，先前已被引入[Lancaster等人，1997]。在本研究中，对TD系统及其1988年Talairach图谱的3-D标签数据库进行了功能激活灶的标记测试。TD系统标签与作者指定的激活坐标标签进行了比较，这些标签来自250多项已发表的功能脑图研究，并与使用这些激活坐标的子集的专家小组的手动图谱衍生标签进行了比较。TD系统的自动标签与作者的标签进行了很好的比较，所有地点的标签匹配率平均为70%或更高。对于大多数网站来说，作者-标签匹配在±5 mm的搜索范围内改进到90%以上。自适应灰质(GM)范围搜索实用程序使用来自M1口区(30名受试者，52个部位)的个体激活进行评估。它在±5 mm的搜索范围内与Brodmann区域标签(BA4和BA6)提供87%的标签匹配。使用自适应GM范围搜索，TD系统与作者标签的总体匹配率(90%)好于专家组(80%)。当与作者对实验的更深入了解结合使用时，TD系统为大脑激活焦点提供一致和全面的标签。TD系统的其他建议应用包括交互式标记、激活灶的解剖分组、病变缺失分析和神经解剖学教育。哼。《脑图》10：120-131,2000。©2000 Wiley-Liss Inc.
An automated coordinate‐based system to retrieve brain labels from the 1988 Talairach Atlas, called the Talairach Daemon (TD), was previously introduced [Lancaster et al., 1997 ]. In the present study, the TD system and its 3‐D database of labels for the 1988 Talairach atlas were tested for labeling of functional activation foci. TD system labels were compared with author‐designated labels of activation coordinates from over 250 published functional brain‐mapping studies and with manual atlas‐derived labels from an expert group using a subset of these activation coordinates. Automated labeling by the TD system compared well with authors' labels, with a 70% or greater label match averaged over all locations. Author‐label matching improved to greater than 90% within a search range of ±5 mm for most sites. An adaptive grey matter (GM) range‐search utility was evaluated using individual activations from the M1 mouth region (30 subjects, 52 sites). It provided an 87% label match to Brodmann area labels (BA 4 & BA 6) within a search range of ±5 mm. Using the adaptive GM range search, the TD system's overall match with authors' labels (90%) was better than that of the expert group (80%). When used in concert with authors' deeper knowledge of an experiment, the TD system provides consistent and comprehensive labels for brain activation foci. Additional suggested applications of the TD system include interactive labeling, anatomical grouping of activation foci, lesion‐deficit analysis, and neuroanatomy education. Hum. Brain Mapping 10:120–131, 2000. © 2000 Wiley‐Liss, Inc.