Preparation and characterization of poly(L-histidine)/poly(L-glutamic acid) multilayer on silicon with nanometer-sized surface structures.
Preparation and characterization of poly(L-histidine)/poly(L-glutamic acid) multilayer on silicon with nanometer-sized surface structures.
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DOI：
10.1016/j.jcis.2012.07.057
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发表时间：
2012-11
影响因子：
9.9
通讯作者：
X. Vinzenz;E. Hüger;M. Himmerlich;S. Krischok;S. Busch;J. Wöllenstein;C. Hoffmann
中科院分区：
文献类型：
--
作者：
X. Vinzenz;E. Hüger;M. Himmerlich;S. Krischok;S. Busch;J. Wöllenstein;C. Hoffmann
表面的具体设计和修改是非常有趣的，特别是对于功能表面和医疗应用。为了在表面上获得薄膜，聚电解质的逐层沉积代表了一种成熟的方法。聚（l-组氨酸）和聚（l-谷氨酸）的交替沉积产生了一个明确的、连续的表面涂层，该涂层使用x射线光电子能谱、傅里叶变换红外光谱、椭偏仪、x射线反射仪、原子力显微镜、扫描电子显微镜、接触角和电动测量进行了全面表征。测量了表面电荷、薄膜生长和最终厚度并进行了交叉验证。此外，还测定了聚电解质在层堆中的化学组成和分布。最后，确定了光学参数，并采用多种方法实现了表面形貌的可视化。这些特征揭示了一层由底层形成的嵌入球体的涂层。这种由（PLH/PGA）8形成的粗糙表面具有很高的可重复性，可能为定制表面的设计提供独特的特征。
The specific design and modification of surfaces is of great interest, especially for functional surfaces and medical applications. In order to obtain films on a surface, the layer-by-layer deposition of polyelectrolytes represents a well-established methodology. The alternating deposition of poly(l-histidine) and poly(l-glutamic acid) results in a defined, continuous surface coating that was thoroughly characterized using X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, ellipsometry, X-ray reflectometry, atomic force microscopy, scanning electron microscopy, contact angle, and electrokinetic measurements. Surface charge, film growth, and final thickness were measured and cross-validated. Additionally, the chemical composition and distribution of polyelectrolytes in the layerstack were determined. Finally, the optical parameters were specified and the surface topography was visualized by several methods. These characterizations revealed a coating with embedded spheroids forming from the bottom layers. This rough surface formed by (PLH/PGA)8was highly reproducible and might provide unique features for the design of tailored surfaces.