Gut Resistome of Preschool Children After Prolonged Mass Azithromycin Distribution: A Cluster-randomized Trial.
Gut Resistome of Preschool Children After Prolonged Mass Azithromycin Distribution: A Cluster-randomized Trial.
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DOI:
10.1093/cid/ciab485
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发表时间:
2021-10-05
期刊:
影响因子:
--
通讯作者:
Doan T
中科院分区:
文献类型:
--
作者:
Arzika AM;Maliki R;Abdou A;Mankara AK;Harouna AN;Cook C;Hinterwirth A;Worden L;Zhong L;Chen C;Ruder K;Zhou Z;Lebas E;O'Brien KS;Oldenburg CE;Le V;Arnold BF;Porco TC;Keenan JD;Lietman TM;Doan T
We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. Although the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs. NCT02047981
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