Advances in the Study of Selenium-Enriched Probiotics: From the Inorganic Se into Se Nanoparticles.
Advances in the Study of Selenium-Enriched Probiotics: From the Inorganic Se into Se Nanoparticles.
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DOI：
10.1002/mnfr.202300432
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发表时间：
2023-10
影响因子：
5.2
通讯作者：
Dan Xiao;Tong Li;Xin Huang;Kongdi Zhu;Zimeng Li;Yulan Dong;Lianshun Wang;Jiaqiang Huang
中科院分区：
文献类型：
--
作者：
Dan Xiao;Tong Li;Xin Huang;Kongdi Zhu;Zimeng Li;Yulan Dong;Lianshun Wang;Jiaqiang Huang
硒是一种重要的金属元素，在生物化学活动中起着不可替代的作用。硒缺乏仍然是全世界面临的营养挑战。补充有机硒是硒缺乏症最有效的治疗手段。由富硒益生菌转化而来的有机硒在抗菌、抗氧化、抗炎、免疫调节等方面表现出突出的优良特性。研究富硒益生菌富硒能力的影响因素及富硒机理，有利于开发更高效的富硒益生菌。富硒益生菌将无机硒转化为硒纳米颗粒（SeNPs），在畜牧业和生物医学领域有着广泛的应用。本文综述了富硒益生菌的研究进展，并对纳米硒颗粒的生物活性进行了评价，展望了其潜在的应用前景。综述了纳米硒在抗氧化方面的优异作用，并阐述了纳米硒改善硒缺乏、促进动物健康的作用机理。
Selenium (Se) is a momentous metallic element that plays an irreplaceable role in biochemical activities. Se deficiency remains a nutritional challenge across the world. Organic Se supplementation is the most effective treatment means for Se deficiency. Organic Se transformed from Se-enriched probiotics show outstanding excellent properties in antibacteria, anti-oxidation, anti-inflammation, and immunoregulation. Studying the influencing factors for Se enrichment capacity and enrichment mechanisms of Se-enriched probiotics is conducive to the exploit of more potent Se-enriched probiotics. Se-enriched probiotics transform inorganic Se into Se nanoparticles (SeNPs), which have been widely used in animal husbandry and biomedical field. In this paper, the novel development of Se-enriched probiotics is reviewed, and the bioactivities of SeNPs are assessed, so as to display their potential application prospects. The excellent role of SeNPs in anti-oxidation is summarized, and the mechanism by which SeNPs improve Se deficiency and boost animal health is explained.