Electrostatically driven complexation of liposomes with a star-shaped polyelectrolyte to low-toxicity multi-liposomal assemblies.
Electrostatically driven complexation of liposomes with a star-shaped polyelectrolyte to low-toxicity multi-liposomal assemblies.
复制标题
静电驱动的脂质体与星形聚电解质络合形成低毒性的多脂质体组件。
DOI：
10.1002/mabi.201300436
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发表时间：
2014
影响因子：
4.6
通讯作者：
F. Menger
中科院分区：
文献类型：
--
作者：
A. Yaroslavov;A. Sybachin;O. V. Zaborova;D. Pergushov;A. Zezin;N. Melik;F. Plamper;A. Müller;F. Menger
阴离子脂质体与星形阳离子脂质体静电复合。复合后，脂质体保持其完整性，所得脂质体-星形复合物在含有0.15 M NaCl的生理溶液中不解离。这提供了可能用作高容量载体的多脂质体容器。
Anionic liposomes are electrostatically complexed to a star-shaped cationic polyelectrolyte. Upon complexation, the liposomes retain their integrity and the resulting liposome-star complexes do not dissociate in a physiological solution with 0.15 M NaCl. This provides a multi-liposomal container for possible use as a high-capacity carrier.