European evidence-based guidelines on pancreatic cystic neoplasms.
European evidence-based guidelines on pancreatic cystic neoplasms.
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DOI：
10.1136/gutjnl-2018-316027
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发表时间：
2018-05
期刊：
影响因子：
24.5
通讯作者：
European Study Group on Cystic Tumours of the Pancreas
中科院分区：
文献类型：
--
作者：
European Study Group on Cystic Tumours of the Pancreas
胰腺囊性肿瘤（PCN）的管理缺乏循证指南。该指南是欧洲胰腺囊性肿瘤研究组、欧洲胃肠病学联合会、欧洲胰腺俱乐部、欧洲-非洲肝胆胰协会、欧洲消化外科和欧洲胃肠内镜学会的联合倡议。它取代了2013年关于多氯化萘的欧洲共识声明准则。欧洲和非欧洲专家进行了系统评价，并使用GRADE方法回答了9个主题（生物标志物、放射学、内镜检查、导管内乳头状粘液性肿瘤（IPMN）、粘液性囊性肿瘤（MCN）、浆液性囊性肿瘤、罕见囊肿、（新）辅助治疗和病理学）的相关临床问题。建议包括保守治疗，手术的相对和绝对适应症。对于无症状MCN和IPMN测量<40 mm且无强化结节，建议采用保守方法。IPMN的相对手术适应证包括主胰管（MPD）直径在5 - 9.9 mm之间或囊肿直径≥40 mm。由于恶性转化的高风险，IPMN的绝对手术适应证包括黄疸，增强壁结节>5 mm，MPD直径>10 mm。建议对适合手术的患者进行终身随访。欧洲PCN循证指南旨在改善PCN的诊断和管理。
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointestinal Endoscopy. It replaces the 2013 European consensus statement guidelines on PCN. European and non-European experts performed systematic reviews and used GRADE methodology to answer relevant clinical questions on nine topics (biomarkers, radiology, endoscopy, intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm, rare cysts, (neo)adjuvant treatment, and pathology). Recommendations include conservative management, relative and absolute indications for surgery. A conservative approach is recommended for asymptomatic MCN and IPMN measuring <40 mm without an enhancing nodule. Relative indications for surgery in IPMN include a main pancreatic duct (MPD) diameter between 5 and 9.9 mm or a cyst diameter ≥40 mm. Absolute indications for surgery in IPMN, due to the high-risk of malignant transformation, include jaundice, an enhancing mural nodule >5 mm, and MPD diameter >10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit for surgery. The European evidence-based guidelines on PCN aim to improve the diagnosis and management of PCN.
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影响因子：
4.5
作者：
Barresi, Luca;Tarantino, Ilaria;Fabbri, Carlo
通讯作者：
Fabbri, Carlo
影响因子：
9.3
作者：
Al-Hadclad, M.;Wallace, M. B.;Raimondo, M.
通讯作者：
Raimondo, M.
DOI：
10.1097/pas.0000000000000533
发表时间：
2015-12
期刊：
The American journal of surgical pathology
影响因子：
--
作者：
Basturk O;Hong SM;Wood LD;Adsay NV;Albores-Saavedra J;Biankin AV;Brosens LA;Fukushima N;Goggins M;Hruban RH;Kato Y;Klimstra DS;Klöppel G;Krasinskas A;Longnecker DS;Matthaei H;Offerhaus GJ;Shimizu M;Takaori K;Terris B;Yachida S;Esposito I;Furukawa T;Baltimore Consensus Meeting
通讯作者：
Baltimore Consensus Meeting
影响因子：
24.5
作者：
Canto MI;Harinck F;Hruban RH;Offerhaus GJ;Poley JW;Kamel I;Nio Y;Schulick RS;Bassi C;Kluijt I;Levy MJ;Chak A;Fockens P;Goggins M;Bruno M;International Cancer of Pancreas Screening (CAPS) Consortium
通讯作者：
International Cancer of Pancreas Screening (CAPS) Consortium
影响因子：
2.1
作者：
Al-Rashdan, Abdullah;Schmidt, C. Max;Dewitt, John
通讯作者：
Dewitt, John