Heritability of alcohol dependence is similar in women and men.
Heritability of alcohol dependence is similar in women and men.
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DOI：
10.1136/ebmental-2012-100670
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发表时间：
2012-08
影响因子：
5.2
通讯作者：
Prescott CA
中科院分区：
文献类型：
--
作者：
Young-Wolff KC;Chereji E;Prescott CA
早期的双胞胎研究得出结论，酒精依赖在女性中的遗传性低于男性，但更大的，最近的研究发现性别之间有类似的遗传贡献。Magnusson等人在瑞典的一个大样本中复制了这一发现，并发现了女性II型酒精依赖的家庭影响证据-这是一种与早发和反社会行为相关的亚型。
Early twin studies concluded that alcohol dependence is less heritable in women than men, but larger, more recent studies find similar genetic contributions in the sexes.1 Magnusson et al replicate this finding in a large Swedish sample and also find evidence for familial influences on type II alcohol dependence in women – a subtype associated with early onset and antisocial behaviour.