Mutagenesis approaches to deduce structure-function relationships in terpene synthases.
Mutagenesis approaches to deduce structure-function relationships in terpene synthases.
复制标题
诱变方法推断萜烯合酶的结构-功能关系。
DOI：
10.1039/b008338k
复制
发表时间：
2003
影响因子：
11.9
通讯作者：
Matsuda,SeiichiPT
中科院分区：
文献类型：
--
作者：
Segura,MichaelJR;Jackson,BethE;Matsuda,SeiichiPT
覆盖范围：截至 2002 年本综述重点介绍了萜烯合酶（特别是倍半萜合酶和氧化角鲨烯环化酶）的诱变研究。这些酶的诱变研究提供了机制见解、特定酶残基的结构-功能关系、新的萜烯结构和具有新活性的酶。回顾了 2002 年为止的文献并引用了 113 篇参考文献。
Covering: up through 2002This review highlights mutagenesis studies of terpene synthases, specifically sesquiterpene synthases and oxidosqualene cyclases. Mutagenesis studies of these enzymes have provided mechanistic insights, structure–function relationships for specific enzymatic residues, novel terpene structures and enzymes with novel activities. The literature through 2002 is reviewed and 113 references cited.