Angiosperm mitochondrial genomes and mutations

Angiosperm mitochondrial genomes and mutations
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DOI:
10.1016/j.mito.2007.10.006
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发表时间:
2008-01-01
期刊:
影响因子:
4.4
通讯作者:
Newton, Kathleen J.
Newton, Kathleen J.
中科院分区:
生物学3区
文献类型:
--
作者:
Kubo, Tornohiko;Newton, Kathleen J.

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开花植物拥有迄今为止报道的最大的线粒体基因组。目前,已有7种被子植物的15个线粒体基因组的核苷酸序列,可以进行详细的比较分析。基因含量在物种之间是可变的,但最显著的特征是基因间区域的流动性,其中物种特异性序列占主导地位。此外,被子植物线粒体基因组,即使在一个物种内,也显示出显著的重排。我们还从基因组的角度回顾了被子植物的线粒体突变,并讨论了它们是如何产生的。核基因在线粒体基因组稳定性和组织中的作用目前正在通过突变体分析得到揭示。(C) 2007 Elsevier B.V.与线粒体研究学会。版权所有。
Flowering plants harbor the largest mitochondrial genomes reported so far. At present, the nucleotide sequences of 15 mitochondrial genomes from seven angiosperm species are available, making detailed comparative analysis feasible. The gene content is variable among the species, but the most striking feature is the fluidity of intergenic regions, where species-specific sequences predominate. Additionally, angiosperm mitochondrial genomes, even within a species, show a remarkable amount of rearrangement. We also review mitochondrial mutants in angiosperms from a genomic viewpoint, and discuss how they have arisen. The involvement of nuclear genes in mitochondrial genome stability and organization is currently being revealed through the analysis-of mutants. (C) 2007 Elsevier B.V. and Mitochondria Research Society. All rights reserved.