Contribution of sialic acid-binding adhesin to pathogenesis of experimental endocarditis caused by Streptococcus gordonii DL1
Contribution of sialic acid-binding adhesin to pathogenesis of experimental endocarditis caused by Streptococcus gordonii DL1
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DOI：
10.1128/iai.74.1.740-743.2006
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发表时间：
2006-01-01
影响因子：
3.1
通讯作者：
Konishi, K
中科院分区：
文献类型：
--
作者：
Takahashi, Y;Takashima, E;Konishi, K
gordonii链球菌DL1唾液酸结合粘附素基因hsa的插入突变导致实验性心内膜炎大鼠主动脉瓣的感染率和炎症反应显著降低，表明粘附素有助于生物体对心脏瓣膜的感染性。
An insertional mutation in hsa, the gene encoding the sialic acid-binding adhesin of Streptococcus gordonii DL1, resulted in a significant reduction of the infection rate of the organism and an inflammatory reaction in the rat aortic valve with experimental endocarditis, suggesting that the adhesin contributes to the infectivity of the organism for heart valves.