Stepwise and dramatic enhancement of anion recognition with a triple-site receptor based on the calix[4]arene framework using two different cationic effectors
Stepwise and dramatic enhancement of anion recognition with a triple-site receptor based on the calix[4]arene framework using two different cationic effectors
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DOI：
10.1021/ja042882y
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发表时间：
2005-04-20
影响因子：
15
通讯作者：
Akine, S
中科院分区：
文献类型：
--
作者：
Nabeshima, T;Saiki, T;Akine, S
Synthesis and binding behavior of a novel multi-responsive host 1, in which two esters, two polyether moieties, two urea sites, and two bipyridine units as ion binding sites are arranged on the calix[4]arene skeleton, is reported. 1 recognizes Na+ and Ag+ simultaneously and quantitatively and captures an anionic guest. The ability of 1 to recognize anions, including CF3SO3- and BF4-, remarkably increases in a stepwise manner using Na+ and Ag+ as effectors. The enhancement of the K. eventually reaches factors of 1500 and 2000 for NO3- and CF3SO3-, respectively, in the presence of both Na+ and Ag+, compared to the free 1. The regulation of binding of multiple ligands may be applicable to multistep cascade systems for the amplification of molecular events, and further studies in this field could provide insight applicable to more advanced molecular devices.
