Effectiveness of acupuncture to treat irritable bowel syndrome: A meta-analysis
Effectiveness of acupuncture to treat irritable bowel syndrome: A meta-analysis
复制标题
针灸治疗肠易激综合征的有效性：荟萃分析。
DOI：
10.3748/wjg.v20.i7.1871
复制
发表时间：
2014-02-21
影响因子：
4.3
通讯作者：
Zhang, Shuo
中科院分区：
文献类型：
--
作者：
Chao, Guan-Qun;Zhang, Shuo
目的：通过随机对照试验的Meta分析，评价针刺治疗肠易激综合征(IBS)的疗效。方法：检索MEDLIINE、PubMed、Scope us、Web of Science、Cochrane Central Register of Control Trials，检索1966-2013年2月期间针刺治疗肠易激综合征的双盲、安慰剂对照试验。根据随机化、对照和报告的可测量结果筛选纳入研究。我们使用改良的Jadad评分来评估文章的质量。采用STATA11.0和Revman5.0软件进行Meta分析。结果：6项随机、安慰剂对照临床试验符合标准，纳入荟萃分析。修改后的Jadad评分为>；3，5篇为高质量文章。我们分析了异质性，发现这些研究在我们的Meta分析中并没有导致异质性。贝格检验P=0.707，艾格检验P=0.334。Meta分析中没有发表偏倚(贝格检验，P=0.707；埃格检验，P=0.334)。从森林地块来看，钻石位于垂直线的右侧，与垂直线没有相交。针刺改善临床疗效的合并相对危险度为1.75(95%CI：1.24~2.46，P=0.001)。使用Stata 11.0和Revman 5.0两种不同的系统，我们证实了针刺治疗IBS的显著疗效。结论：针刺对IBS症状的控制具有临床意义和统计学意义。(C)2014年白石登出版集团有限公司。版权所有。
AIM: To evaluate the efficacy of acupuncture for treatment of irritable bowel syndrome (IBS) through meta-analysis of randomized controlled trials.METHODS: We searched MEDLIINE, PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials from 1966 to February 2013 for doubleblind, placebo-controlled trials investigating the efficacy of acupuncture in the management of IBS. Studies were screened for inclusion based on randomization, controls, and measurable outcomes reported. We used the modified Jadad score for assessing the quality of the articles. STATA 11.0 and Revman 5.0 were used for meta-analysis. Publication bias was assessed by Begg's and Egger's tests.RESULTS: Six randomized, placebo-controlled clinical trials met the criteria and were included in the metaanalysis. The modified Jadad score of the articles was > 3, and five articles were of high quality. We analyzed the heterogeneity and found that these studies did not cause heterogeneity in our meta-analysis. Begg's test showed P = 0.707 and Egger's test showed P = 0.334. There was no publication bias in our meta-analysis (Begg's test, P = 0.707; Egger's test, P = 0.334). From the forest plot, the diamond was on the right side of the vertical line and did not intersect with the line. The pooled relative risk for clinical improvement with acupuncture was 1.75 (95% CI: 1.24-2.46, P = 0.001). Using the two different systems of STATA 11.0 and Revman 5.0, we confirmed the significant efficacy of acupuncture for treating IBS.CONCLUSION: Acupuncture exhibits clinically and statistically significant control of IBS symptoms. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.