DECREASED CEREBROSPINAL-FLUID GLUTAMINE LEVELS IN PATIENTS WITH BENIGN BRAIN-TUMORS
DECREASED CEREBROSPINAL-FLUID GLUTAMINE LEVELS IN PATIENTS WITH BENIGN BRAIN-TUMORS
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DOI：
10.1111/j.1471-4159.1985.tb04066.x
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发表时间：
1985-01-01
影响因子：
4.7
通讯作者：
ALMEFTY, O
中科院分区：
文献类型：
--
作者：
ELYAZIGI, A;ALMEFTY, O
CSF glutamine concentrations were studied in 12 patients with benign brain tumors (meningioma, craniopharyngioma or osteofibroma), 12 patients with malignant brain tumors (astrocytoma, medulloblastoma, pinealoblastoma or chondrosarcoma), 9 patients with noncerebral tumors, and a reference group of 24 patients. The mean .+-. SD levels in the benign tumor group (424 .+-. 124 .mu.M) were significantly lower (P < 0.0004) than those in the reference group (642 .+-. 195 .mu.M). There was no significant difference between the CSF glutamine concentrations in the malignant cerebral tumor group (643 .+-. 210 .mu.M) or noncerebral tumor group (599 .+-. 127 .mu.M) and those in the reference group. In patients with benign brain tumors there was indication of an inverse linear relationship between the logarithm of CSF glutamine concentration and tumor diameter.
