Alcohol consumption and obesity: The hidden scare with COVID-19 severity

Alcohol consumption and obesity: The hidden scare with COVID-19 severity
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DOI:
10.1016/j.mehy.2020.110272
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发表时间:
2020-11-01
期刊:
影响因子:
4.7
通讯作者:
Fatima, Syeda Sadia
Fatima, Syeda Sadia
中科院分区:
医学4区
文献类型:
--
作者:
Bilal, Bushra;Saleem, Faizan;Fatima, Syeda Sadia

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肥胖者似乎是感染COVID-19的最高风险。此外,与发展中国家相比,发达国家的发病率和死亡率更高。造成这种差异的一个可能原因可能是生活条件和接触其他感染的差异。其次,食物的差异,尤其是饮酒,可能会导致肥胖症的恶化。我们的假设表明,饮酒和肥胖的结合导致免疫力低下,并使个体易于发展“细胞因子风暴”和“急性呼吸窘迫综合征”;这是COVID-19死亡率和发病率的标志。因此,我们建议减少任何一个触发因素都可以在对抗疾病严重程度方面产生有益的影响。
Obese individuals seem to be at the highest risk of contracting COVID-19 infection. Furthermore, severity of morbidity and mortality rates are higher in the developed world as compared to the developing world. One probable reason for this difference could be the difference in living conditions and exposure to other infections. Secondly, the difference in food especially, alcohol use may have deteriorating effects superimposed with obesity. Our hypothesis suggests that a combination of alcohol consumption and obesity causes low immunity and makes the individual prone to develop 'cytokine storm' and 'acute respiratory distress syndrome'; the hallmark of COVID-19 mortality and morbidity. Thus, we propose that reducing any one trigger can have a beneficial effect in combating the disease severity.