The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use
The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use
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DOI：
10.1176/appi.ajp.160.7.1320
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发表时间：
2003-07-01
影响因子：
17.7
通讯作者：
Moras, K
中科院分区：
文献类型：
--
作者：
Weiss, RD;Griffin, ML;Moras, K
目的：在可卡因依赖治疗期间定期测量渴望可以监测患者的临床状态，并可能评估他们在不久的将来使用药物的风险。有效的治疗可以通过帮助患者在高度渴望的情况下戒酒来减少渴望和随后的药物使用之间的相关性。本研究探讨了可卡因的渴望，心理治疗，可卡因的使用在随后的week.Method：在国家药物滥用研究所的合作可卡因治疗研究，比较了四种心理治疗可卡因依赖，一个三项的渴望问卷每周给449例患者，看看它是否预测可卡因的使用在随后的一周。自我报告和尿液screening.Results：与控制前一周的可卡因使用，更高的综合得分的渴望问卷与可卡因使用的可能性更大，在随后的一周，每增加1分的渴望问卷的综合得分增加可卡因使用的可能性在随后的一周增加10%。然而，在接受个人加团体药物咨询的患者中，最好的整体可卡因使用结果的治疗条件，增加渴望分数与可卡因使用在随后的week.Conclusions更大的可能性无关：三项可卡因渴望问卷预测可卡因使用的相对可能性在随后的一周。此外，渴望和随后的可卡因使用之间的关系因治疗条件而异，这表明研究中最有效的治疗可能削弱了渴望和随后使用之间的联系。
Objective: Regular measurement of craving during treatment for cocaine dependence can monitor patients' clinical status and potentially assess their risk for drug use in the near future. Effective treatment can reduce the correlation between craving and subsequent drug use by helping patients abstain despite high craving. This study examined the relationship between cocaine craving, psychosocial treatment, and cocaine use in the ensuing week.Method: In the National Institute on Drug Abuse Collaborative Cocaine Treatment Study, which compared four psychosocial treatments for cocaine dependence, a three-item craving questionnaire was administered weekly to 449 patients to see whether it predicted cocaine use in the ensuing week. Cocaine use was assessed with self-reports and urine screening.Results: With control for the previous week's cocaine use, a higher composite score on the craving questionnaire was associated with greater likelihood of cocaine use in the subsequent week; each 1-point increase on the composite score of the craving questionnaire increased the likelihood of cocaine use in the ensuing week by 10%. However, among patients who received individual plus group drug counseling, the treatment condition with the best overall cocaine use outcome, increased craving scores were not associated with greater likelihood of cocaine use in the subsequent week.Conclusions: A three-item cocaine craving questionnaire predicted the relative likelihood of cocaine use during the subsequent week. Moreover, the relationship between craving and subsequent cocaine use varied by treatment condition, suggesting that the most effective treatment in the study might have weakened the link between craving and subsequent use.