Roles for novel pharmacological blockers of aquaporins in the treatment of brain oedema and cancer
Roles for novel pharmacological blockers of aquaporins in the treatment of brain oedema and cancer
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DOI：
10.1111/j.1440-1681.2009.05244.x
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发表时间：
2010-04
影响因子：
2.9
通讯作者：
A. Yool;E. A. Brown;G. Flynn
中科院分区：
文献类型：
--
作者：
A. Yool;E. A. Brown;G. Flynn
1. 水通道蛋白（AQPs）是基础研究和医学药物发现的靶点。涉及体液失衡和水肿的人类疾病是主要关注的问题，并涉及aqp表达的组织。随着该领域研究的不断深入，AQPs的功能特性范围也在稳步扩大。
1. Aquaporins (AQPs) are targets for drug discovery for basic research and medicine. Human diseases involving fluid imbalances and oedema are of major concern and involve tissues in which AQPs are expressed. The range of functional properties of AQPs is continuing to expand steadily with ongoing research in the field.