Children in south Asia have higher body mass-adjusted blood pressure levels than white children in the United States - A comparative study
Children in south Asia have higher body mass-adjusted blood pressure levels than white children in the United States - A comparative study
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DOI：
10.1161/01.cir.0000157699.87728.f1
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发表时间：
2005-03-15
期刊：
影响因子：
37.8
通讯作者：
Chaturvedi, N
中科院分区：
文献类型：
--
作者：
Jafar, TH;Islam, M;Chaturvedi, N
背景-儿童期血压是成人期血压的一个既定预测指标，而成人期血压反过来又会增加心血管疾病的死亡率。与白人相比，南亚成年人特别容易患心血管疾病，但南亚儿童高血压的患病率和血压的决定因素尚未被探索或与白色儿童进行比较.方法和结果-对5641名5至14岁的南亚儿童进行分析，这些儿童包括在巴基斯坦全国代表性的全国健康调查中（NHSP）（1990 - 1994年）和第三次全国健康和营养调查（NHANES III）（1988 - 1994年）中包括的4 756名5至14岁的白色儿童。获得人体测量数据。血压测量两次，在坐姿与水银血压计和适当大小的袖带。高血压定义为收缩压或舒张压水平>=美国人群年龄、性别和身高百分位数特定参考水平的第95百分位数。通过线性回归分析比较2组数据中儿童的平均体重指数（BMI）校正血压值。南亚5至14岁儿童的高血压总体患病率（95% CI）为12.2%（11.3%至13.1%）：男孩为15.8%（14.5%至17.1%），女孩为8.7%（7.6%至9.8%）。这与美国儿童高血压患病率预测值5%形成鲜明对比（P <0.001）。BMI校正的平均收缩压水平（SD）分别为100（11）和99（11）mm Hg（P <0.001），舒张压水平（SD）分别为63（10）和52（12）mm Hg（P <0.001）NHSP与NHANES III，结论：南亚儿童的体重调整后血压水平高于美国的白色儿童。需要进一步的研究来确定造成这些差异的因素。需要立即注意解决南亚本地儿童的高血压及其危险因素。
Background - Blood pressure during childhood is an established predictor of adult blood pressure, which in turn increases mortality as a result of cardiovascular disease. Adult South Asian populations are particularly predisposed to cardiovascular disease compared with whites, but the prevalence of high blood pressure and determinants of blood pressure in South Asian children have not been explored or compared with those of white children.Methods and Results - Analyses were performed on 5641 South Asian children 5 to 14 years old included in the nationally representative National Health Survey of Pakistan (NHSP) (1990 - 1994) and on 4756 white children 5 to 14 years old included in Third National Health and Nutrition Examination Survey (NHANES III) (1988 - 1994). Anthropometric measurements were obtained. Blood pressure was measured twice in the seated position with a mercury sphygmomanometer and an appropriate-size cuff. High blood pressure was defined as a systolic or diastolic blood pressure level that was >= 95th percentile of age-, sex-, and height- percentile - specific reference level for the US population. Mean body mass index (BMI) - adjusted blood pressure values were compared among children in 2 data sets by use of linear regression analysis. The overall prevalence (95% CI) of high blood pressure in South Asian children 5 to 14 years old was 12.2% (11.3% to 13.1%): 15.8% (14.5% to 17.1%) in boys and 8.7% (7.6% to 9.8%) in girls. This is in sharp contrast with the predicted 5% prevalence of high blood pressure in children in the United States (P < 0.001). The mean BMI-adjusted systolic blood pressure levels (SD) were 100 (11) versus 99 (11) mm Hg (P < 0.001), and diastolic blood pressure levels (SD) were 63 (10) versus 52 (12) mm Hg (P < 0.001) in NHSP versus NHANES III, respectively.Conclusions - South Asian children have higher body-mass - adjusted blood pressure levels than white children in the United States. Further studies are needed to determine factors responsible for these differences. Immediate attention is needed to address high blood pressure and its risk factors in native South Asian children.