Chorionic villus sampling in continuing pregnancies. I. Low fetal loss rates in initial 109 cases.
Chorionic villus sampling in continuing pregnancies. I. Low fetal loss rates in initial 109 cases.
复制标题
连续妊娠中的绒毛膜绒毛取样。
DOI：
10.1016/0002-9378(86)90723-4
复制
发表时间：
1986
影响因子：
9.8
通讯作者：
Baum,LD
中科院分区：
文献类型：
--
作者：
Elias,S;Simpson,JL;Martin,AO;Sabbagha,R;Bombard,A;Rosinsky,BJ;Baum,LD
在接受咨询并给予知情同意后同意进行绒毛膜绒毛取样的前150名妇女中，41名被证明不合格。在其余109例进行绒毛取样的病例中，有6例（5.5%）未能获得足够数量的绒毛进行诊断性检测。在单胎流产中，取样后2周确认胎儿存活;然而，3周后胎儿死亡变得明显。4例（3.7%）因结果异常终止妊娠，1例（0.9%）在结果正常后选择终止妊娠。在41例已完成的妊娠中，婴儿无明显异常。有两名早产;其中一名婴儿在妊娠29周时胎膜早破，出生后不久死亡。所有未交付的案件在提交时进展正常。
Among the first 150 women who agreed to have chorionic villus sampling after receiving counseling and giving informed consent, 41 proved ineligible. In six (5.5%) of the remaining 109 cases in which chorionic villus sampling was performed, we were unsuccessful in obtaining an adequate amount of villi to permit diagnostic testing. In the single loss, fetal viability was confirmed 2 weeks after sampling; however, fetal death became evident 3 weeks later. In four (3.7%) cases the pregnancies were terminated because of abnormal results, and in one (0.9%) case the pregnancy was electively terminated after normal results. Among the 41 completed pregnancies no anomalies were evident in the infants. There were two premature deliveries; one of these two infants died shortly after birth following premature rupture of the membranes at 29 weeks' gestation. All undelivered cases were progressing normally at the time of submission.