Six-year effect of depressive symptoms on the course of physical disability in community-living older adults
Six-year effect of depressive symptoms on the course of physical disability in community-living older adults
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DOI：
10.1001/archinte.160.20.3074
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发表时间：
2000-11-13
影响因子：
--
通讯作者：
Evans, DA
中科院分区：
文献类型：
--
作者：
Cronin-Stubbs, D;de Leon, CFM;Evans, DA
背景：晚年抑郁症影响身体健康并阻碍身体残疾的恢复。但在普通人群中频繁出现的较轻微症状是否会增加患残疾的风险或降低康复的可能性仍不清楚。 目的：检查轻度抑郁症状的影响，通过流行病学研究中心抑郁量表的简化版本（10个项目，范围从0-10）评估，对身体残疾过程的影响，通过Katz日常Livinag活动量表、Rosow-Breslau功能健康量表、Nagi的项目进行评估指数.方法：进行了一项基于人群的纵向研究，对马萨诸塞州东波士顿 3434 名 65 岁及以上的社区居民进行了 6 次后续访谈。结果：每增加一种抑郁症状，残疾的可能性就会增加（对于 Katz 测量：每种症状的比值比为 1.16；95% 置信区间为 1.13-1.19；对于 Rosow-Breslau 测量：比值比， 1.14；95% 置信区间，1.111.16；对于 Nagi 测量：优势比，1.17；95% 置信区间，1.14-1.19)。随着抑郁症状数量的增加，从身体残疾中恢复的可能性降低（对于 Katz 测量：比值比，0.96；95% 置信区间，0.93-0.99；对于 Rosow-Breslau 测量：比值比，0.86；95% 置信区间，0.84-0.89；对于 Nagi 测量：比值比，0.89；95% 置信区间， 0.87-0.91）。这种影响并未受到年龄、性别、受教育程度、体重指数或慢性健康状况的影响。结论：老年人（年龄大于或等于 65 岁）的轻度抑郁症状与残疾可能性增加和康复机会降低相关，无论年龄、性别和其他导致身体残疾的因素如何。
Background: Late-life depression affects physical health and impedes recovery from physical disability. But whether milder symptoms that occur frequently in the general population increase the risk of developing a disability or decrease the likelihood of recovery remains unclear.Objective: To examine the effect of mild symptoms of depression, assessed by a reduced version (10 items, ranging from 0-10) of the:Center for Epidemiological Studies-Depression Scale, on the course of physical disability, assessed by items from the Katz Activities of Daily Livinag Scale, the Rosow-Breslau Functional Health Scale, an the Nagi Index.Methods: A population-based longitudinal study was conducted, with 6 follow up interviews of 3434 community-dwelling persons aged 65 years and older in East Boston, Mass.Results: The likelihood of becoming disabled increased with each additional symptom of depression (for the Katz measure: odds ratio, 1.16 per symptom; 95% confidence interval, 1.13-1.19; for the Rosow-Breslau measure: odds ratio, 1.14; 95% confidence interval, 1.111.16; and for the Nagi measure: odds ratio, 1.17; 95% confidence interval, 1.14-1.19). As the number of depressive symptoms increased, the likelihood of recovering from a physical disability decreased (for the Katz measure: odds ratio, 0.96; 95% confidence interval, 0.93-0.99; for the Rosow-Breslau measure: odds ratio, 0.86; 95% confidence interval, 0.84-0.89; and for the Nagi measure: odds ratio, 0.89; 95% confidence interval, 0.87-0.91). This effect was not accounted for by age, sex, level of educational attainment, body mass index, or chronic health conditions.Conclusion: Mild depressive symptoms in older persons (those aged greater than or equal to 65 years) are associated with an increased likelihood of becoming disabled and a decreased chance of recovery, regardless of age, sex, and other factors that contribute to physical disability.