Surgical results for small cell lung cancer based on the new TNM staging system
Surgical results for small cell lung cancer based on the new TNM staging system
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DOI：
10.1016/s0003-4975(00)01401-6
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发表时间：
2000-11-01
影响因子：
4.6
通讯作者：
Matsuda, H
中科院分区：
文献类型：
--
作者：
Inoue, M;Miyoshi, S;Matsuda, H
背景资料。手术联合化疗最近被推荐用于无淋巴结转移的极早期小细胞肺癌。根据新的国际分期标准，对91例小细胞肺癌患者行肺切除的临床资料进行回顾性分析。5年总体生存概率为37.1%。P期0期、P期IA、P期IB、P期IIA、P期IIB的5年生存率分别为100%、56.1%、30.0%、57.1%、42.9%。在完全切除的P期IA-IIB患者中，手术加化疗的5年生存率好于单纯手术治疗的患者。此外，化疗4个疗程或以上者的5年生存率为80.0%。这些结果表明，对于P期IA-IIB期患者，应考虑手术治疗，对于这些可切除的病例，联合化疗可能是可取的。(Ann Thorac Surg 2000；70：1615-9)(C)2000年，由胸外科学会出版。
Background. Operation with combined chemotherapy has been recently recommended for very early stage of small cell lung cancer without lymph node metastasis.Methods. A retrospective study was undertaken in 91 patients who had undergone pulmonary resection for small cell lung cancer according to the new international staging system.Results. The 5-year overall probability of survival was 37.1%. The 5-year survival rate was 100% for p-stage 0, 56.1% for p-stage IA, 30.0% for p-stage IB, 57.1% for p-stage IIA, and 42.9% for p-stage IIB. In the p-stage IA-IIB patients who underwent a complete resection, the 5-year survival rate of the patients treated by operation with chemotherapy was better than that of patients treated by operation alone. In addition, the 5-year survival rate of the patients who had four or more courses of chemotherapy was 80.0%.Conclusions. These results suggest that operation should be considered for p-stage IA-IIB patients and more than four courses of combined chemotherapy might be desirable in these resectable cases. (Ann Thorac Surg 2000;70:1615-9) (C) 2000 by The Society of Thoracic Surgeons.