Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.
Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.
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DOI：
10.1128/genomea.01394-15
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发表时间：
2015-11-25
期刊：
影响因子：
--
通讯作者：
Mooi FR
中科院分区：
文献类型：
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作者：
Bart MJ;van der Heide HG;Zeddeman A;Heuvelman K;van Gent M;Mooi FR
病原体的适应导致了百日咳的死灰复燃。为了便于我们理解这种适应，我们在此报告了代表大流行 ptxP3 谱系的 11 个完全封闭且带注释的百日咳博德特氏菌基因组。我们的分析包括六种不产生疫苗成分百日咳杆菌粘附素和/或丝状血凝素的菌株。
Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin.