The Sino-Nasal Outcome Test (SNOT): Can we make it more clinically meaningful?
The Sino-Nasal Outcome Test (SNOT): Can we make it more clinically meaningful?
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DOI：
10.1016/j.otohns.2007.01.024
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发表时间：
2007-05-01
影响因子：
3.4
通讯作者：
Cano, Stefan J.
中科院分区：
文献类型：
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作者：
Browne, John Patrick;Hopkins, Claire;Cano, Stefan J.
目的：探讨在分析鼻疗效试验（SNOT）时是否应该使用亚量表。研究设计和背景：前瞻性队列研究涉及英格兰和威尔士的87家NHS急症医院。结果：通过探索性因子分析，我们发现了SNOT中存在四个独特结构的证据。两个结构处理症状（鼻和耳/面部）和两个处理与健康相关的生活质量方面（心理问题和睡眠功能）。与这些结构相对应的SNOT亚量表提供了比SNOT总分所提供的关于不同鼻-鼻疾病患者获得的手术获益类型的临床有意义的信息。结论：SNOT不是单维的，SNOT总分可以掩盖真实基础构形的差异。意义：如果采用适当的亚量表对SNOT进行评分，将大大提高其临床应用。这样的措施将使我们梳理出不同的鼻腔条件的影响，除了允许更好地了解治疗效果。(C) 2007年美国耳鼻喉头颈外科学会基金会。版权所有。
OBJECTIVE: To test whether subscales should be used when analyzing the Sino-Nasal Outcome Test (SNOT).STUDY DESIGN AND SETTING: Prospective cohort study involved 87 acute NHS hospitals in England and Wales.RESULTS: With the use of exploratory factor analysis we found evidence for the existence of four unique constructs within the SNOT. Two constructs address symptoms (rhinologic and ear/ facial) and two address aspects of health-related quality of life (psychological issues and sleep function). Subscales of the SNOT that correspond to these constructs provided clinically meaningful information over and above that provided by the SNOT total score on the type of surgical benefits gained by patients with different sino-nasal conditions.CONCLUSION: The SNOT is not unidimensional and a SNOT total score will mask variation in the true underlying constructs.SIGNIFICANCE: The SNOT would have greatly improved clinical use if it was scored with appropriate subscales. Such a measure would allow us to tease out the differential impact of sino-nasal conditions, in addition to allowing greater understanding of treatment effects. (C) 2007 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.