An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane.
An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane.
复制标题
白细胞和成纤维细胞在布鲁赫膜破裂中作用的超微结构研究。
DOI：
10.1111/j.1442-9071.1984.tb01120.x
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Shirley Sarks Fraco
中科院分区：
文献类型：
--
作者：
P. Penfold;Murray Killingsworth BSppSc;Shirley Sarks Fraco
根据光镜分类选择30只眼进行超微结构检查，以代表黄斑变性的所有阶段。这只眼睛属于29名死亡时年龄在40岁至91岁之间的患者，除这名40岁的患者外，所有患者都曾在生前接受过检查。结果表明，单核细胞、淋巴细胞、成纤维细胞和肥大细胞在黄斑变性早期和晚期Bruchs膜断裂的形成中可能起一定作用。在脉络膜新生血管的可能作用的背景下，这些观察结果的含义被讨论。
Ultrastructural examination was performed on 30 eyes selected on the basis of a light microscopic classification as representing all stages of macular degeneration. The eyes belonged to 29 patients aged 40 to 91 years at death and all patients with the exception of the 40-year-old had been examined during life. The results indicate that monocytes, lymphocytes, fibroblasts and mast cells may play a role in the formation of breaks in Bruch's membrane at early and late stages of macular degeneration. The implications of these observations are discussed in the context of their possible role in choroidal neovascularization.
通过巨噬细胞衍生的生长因子刺激非淋巴间充质细胞增殖。
DOI：
--
发表时间：
1981
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Martin,BM;GimbroneJr,MA;Unanue,ER;Cotran,RS
通讯作者：
Cotran,RS