Sensitive analysis of DNA methyltransferase based on a hairpin-shaped DNAzyme.
Sensitive analysis of DNA methyltransferase based on a hairpin-shaped DNAzyme.
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DOI：
10.1039/c2cc35648a
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发表时间：
2012-09
影响因子：
4.9
通讯作者：
Tian Tian-Tian;Heng Xiao;Yuelin Long;Xiaoe Zhang;Shaoru Wang;Xiang Zhou;Songmei Liu;Xin Zhou
中科院分区：
文献类型：
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作者：
Tian Tian-Tian;Heng Xiao;Yuelin Long;Xiaoe Zhang;Shaoru Wang;Xiang Zhou;Songmei Liu;Xin Zhou
The analysis of DNA methylation and MTase (methyltransferase) activity is important in epigenetic study. We have developed a novel strategy for sensitive analysis of MTase activity based on a hairpin shaped DNAzyme; 8-17 DNAzyme amplicon has been adopted and found to be very effective in such analysis.
