Common lizards break Dollo's law of irreversibility: genome-wide phylogenomics support a single origin of viviparity and re-evolution of oviparity
Common lizards break Dollo's law of irreversibility: genome-wide phylogenomics support a single origin of viviparity and re-evolution of oviparity
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普通蜥蜴打破了多洛不可逆定律：全基因组系统基因组学支持胎生的单一起源和卵生的再进化
DOI：
10.1101/225086
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Recknagel H
中科院分区：
文献类型：
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作者：
Recknagel H
多洛的不可逆定律指出，一旦一个复杂的特征在进化中丢失，它就无法重新获得。人们认为，复杂的上位性相互作用和发育限制阻碍了这种特征的重新出现。卵生生殖（产卵）需要蛋壳的形成，代表了这种复杂性状的一个例子。在爬行动物中，胎生（活产）已经反复进化，但如果卵生可以重新进化，这是非常有争议的。在这里，我们使用多达194，358个SNP位点和1，334，760 bp的序列，重建了常见蜥蜴胎生和卵生谱系的生殖系统，并推断了产次模式的进化历史。我们的进化史支持六个主要的常见蜥蜴谱系，这些谱系以前已经被确定。我们发现强有力的统计支持的拓扑结构的安排，这表明从胎生逆转卵生。我们的拓扑结构是一致的高度分化的染色体构型之间的血统，但不同意与以前的系统发育研究在一些节点。虽然我们发现了对卵生逆转的高度支持，但需要更多的基因组和发育数据来有力地测试这一点，并评估逆转可能发生的机制。
Dollo’s law of irreversibility states that once a complex trait has been lost in evolution, it cannot be regained. It is thought that complex epistatic interactions and developmental constraints impede the re-emergence of such a trait. Oviparous reproduction (egg-laying) requires the formation of an eggshell and represents an example of such a complex trait. In reptiles, viviparity (live-bearing) has evolved repeatedly but it is highly disputed if oviparity can re-evolve. Here, using up to 194,358 SNP loci and 1,334,760 bp of sequence, we reconstruct the phylogeny of viviparous and oviparous lineages of common lizards and infer the evolutionary history of parity modes. Our phylogeny supports six main common lizard lineages that have been previously identified. We find strong statistical support for a topological arrangement that suggests a reversal to oviparity from viviparity. Our topology is consistent with highly differentiated chromosomal configurations between lineages, but disagrees with previous phylogenetic studies in some nodes. While we find high support for a reversal to oviparity, more genomic and developmental data are needed to robustly test this and assess the mechanism by which a reversal might have occurred.