Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities
Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities
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DOI：
10.1377/hlthaff.2015.1476
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发表时间：
2016-08-01
期刊：
影响因子：
9.7
通讯作者：
Ordovas, Jose M.
中科院分区：
文献类型：
--
作者：
Smith, Caren E.;Fullerton, Stephanie M.;Ordovas, Jose M.
有证据表明，生物和非生物因素都造成了健康差距。特别是遗传学，在常见疾病如何表现自己方面发挥了作用。今天，基于基因的诊断和治疗的前所未有的进步为个性化医疗提供了机会。然而，弱势群体可能无法获得这些进步，基于非西班牙裔白人研究的治疗可能无法推广到少数群体成员。除非遗传技术能够普及，否则现有的差距可能会扩大。解决这一问题需要综合战略，包括扩大遗传研究，提高遗传知识水平，并以避免污名化等伤害的方式增加少数群体获得遗传技术的机会。
Evidence shows that both biological and nonbiological factors contribute to health disparities. Genetics, in particular, plays a part in how common diseases manifest themselves. Today, unprecedented advances in genetically based diagnoses and treatments provide opportunities for personalized medicine. However, disadvantaged groups may lack access to these advances, and treatments based on research on non-Hispanic whites might not be generalizable to members of minority groups. Unless genetic technologies become universally accessible, existing disparities could be widened. Addressing this issue will require integrated strategies, including expanding genetic research, improving genetic literacy, and enhancing access to genetic technologies among minority populations in a way that avoids harms such as stigmatization.