A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity.
A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity.
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DOI：
10.1002/anie.201505464
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发表时间：
2015-11-09
期刊：
影响因子：
--
通讯作者：
Goldup SM
中科院分区：
文献类型：
--
作者：
Galli M;Lewis JE;Goldup SM
研制了轮烷基Au催化剂，并研究了机械键对其催化性能的影响。与非互锁的线程，轮烷需要一个催化无辜的辅因子，其身份显着影响反应的产率和非对映选择性。在优化的条件下，AuI（催化剂）、AgI（提取Cl−配体）和CuI（辅因子）结合联合收割机，产生具有优异活性和选择性的催化剂。
A rotaxane-based Au catalyst was developed and the effect of the mechanical bond on its behavior was studied. Unlike the non-interlocked thread, the rotaxane requires a catalytically innocent cofactor, the identity of which significantly influences both the yield and diastereoselectivity of the reaction. Under optimized conditions, AuI (the catalyst), AgI (to abstract the Cl− ligand), and CuI (the cofactor) combine to produce a catalyst with excellent activity and selectivity.