Concordance of cancer patients' function, symptoms, and supportive care needs

Concordance of cancer patients' function, symptoms, and supportive care needs
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DOI:
10.1007/s11136-009-9519-6
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发表时间:
2009-10-01
影响因子:
3.5
通讯作者:
Wu, Albert W.
Wu, Albert W.
中科院分区:
医学2区
文献类型:
--
作者:
Snyder, Claire F.;Garrett-Mayer, Elizabeth;Wu, Albert W.

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虽然患者的功能、症状和支持性护理需求明显相关,但更好地了解这些关系可以改善患者管理。在这项横断面观察性研究中,117名癌症患者完成了支持性护理需求调查-34和EORTC-QLQ-C30。EORTC-QLQ-C30的每个症状和功能域使用参考样本平均分数的截止值进行二分类(高与低)。每个需求域使用代表未满足需求的平均分数的截止值进行二分类。我们利用潜在类别分析探索了患者内部的功能模式、症状和需求域。基于这些模式,患者被分为高功能和低功能;高症状和低症状;高需求和低需求。我们检查了患者功能、症状和需求分类之间的一致性。66例(56%)患者的功能、症状和需求分类一致。在至少一个部位有缺陷的患者(n = 68)中,51例(75%)患者的分类不一致。大约50%的患者在功能水平、症状和需求方面有相似的分类,但在至少一个领域有缺陷的患者中,不一致是常见的,这强调了评估所有这些结果作为患者评估的一部分的重要性。
Although patients' function, symptoms, and supportive care needs are obviously related, a better understanding of these relationships could improve patient management.In this cross-sectional, observational study, 117 cancer patients completed the Supportive Care Needs Survey-34 and EORTC-QLQ-C30. Each symptom and function domain from the EORTC-QLQ-C30 was dichotomized (high vs. low) using a cut-off of reference sample mean scores. Each need domain was dichotomized using a cut-off of an average score representing an unmet need. We explored within-patient patterns of function, symptom, and need domains using latent class analysis. Based on these patterns, patients were categorized as high versus low function; high versus low symptom; and high versus low need. We examined the concordance between categorizations of patients' function, symptoms, and needs.The categorizations of function, symptoms, and needs were concordant for 66 patients (56%). Among patients with deficits in at least one area (n = 68), categorizations for 51 patients (75%) were discordant.About 50% of patients have similar classifications of their level of function, symptoms, and needs, but discordance was common among patients with deficits in at least one area, emphasizing the importance of assessing all of these outcomes as part of patient evaluations.