ASYMMETRIC DISTRIBUTION OF DENSE BANDS IN MUSCLE-CELLS OF MAMMALIAN ARTERIOLES
ASYMMETRIC DISTRIBUTION OF DENSE BANDS IN MUSCLE-CELLS OF MAMMALIAN ARTERIOLES
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DOI：
10.1016/s0022-5320(83)90083-7
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发表时间：
1983-01-01
期刊：
影响因子：
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通讯作者：
GABELLA, G
中科院分区：
文献类型：
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作者：
GABELLA, G
本文用电镜观察了小鼠、大鼠、豚鼠、家兔、绵羊和猪的内脏小动脉。在所研究的所有器官和物种中，图尼卡中膜的肌细胞排列成紧密的螺旋状，并形成几个完整的圈。肌丝也大致沿圆周排列，尽管同一细胞不同区域的肌丝束之间往往有一点分歧。致密带很明显，将肌丝锚在细胞膜上;它们在面向外膜的细胞膜区域比面向内膜的区域明显更大，数量更多。这种不对称的分布被解释为是管腔收缩的有效机制所必需的。
Arterioles from viscera of mice, rats, guinea pigs, rabbits, sheep and pigs were examined by EM. In all the organs and species investigated the muscle cells of the tunica media are arranged in tight helices and make several full turns. The myofilaments also are arranged approximately circumferentially, although there is often a little divergence between bundles of myofilaments in different areas of the same cell. The dense bands are conspicuous and anchor the myofilaments to the cell membrane; they are markedly larger and more numerous on the regions of the cell membrane facing the adventitia than on those facing the intima. This asymmetrical distribution is interpreted as essential to an efficient mechanism for constriction of the lumen.