Restoring knee joint kinematics after anterior cruciate ligament injury might inhibit synovial membrane inflammation.
Restoring knee joint kinematics after anterior cruciate ligament injury might inhibit synovial membrane inflammation.
复制标题
前交叉韧带损伤后恢复膝关节运动学可能会抑制滑膜炎症。
DOI：
10.1007/s11332-018-0481-y
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发表时间：
2018
影响因子：
1.5
通讯作者：
Kanemura N
中科院分区：
文献类型：
--
作者：
Murata K;Kokubun T;Takayanagi K;Kanemura N
我们开发了一种新的受控异常关节运动（CAJM）模型，用于控制传统前交叉韧带横断（ACL-T）后的不稳定性。我们使用我们新的CAJM大鼠模型评估关节不稳定阻尼是否抑制骨关节炎患者的滑膜炎症。我们发现，大鼠的关节不稳定性在ACL-T和CAJM模型之间是不同的。关节不稳定可能导致滑膜炎并抑制骨关节炎。
We developed a novel controlled abnormal joint movement (CAJM) model that controls instability after traditional anterior cruciate ligament transection (ACL-T). We evaluated whether joint instability damping suppresses synovial inflammation in osteoarthritis patients using our new CAJM rat model. We found that joint instability in rats differed between the ACL-T and CAJM models. Joint instability might contribute to synovitis and inhibit osteoarthritis.