Structure and function of the global ocean microbiome
Structure and function of the global ocean microbiome
复制标题
DOI：
10.1126/science.1261359
复制
发表时间：
2015-05-22
期刊：
影响因子：
56.9
通讯作者：
Bork, Peer
中科院分区：
文献类型：
--
作者：
Sunagawa, Shinichi;Coelho, Luis Pedro;Bork, Peer
微生物是地球化学过程的主要驱动力，但绘制功能多样性，微生物群落结构及其生态决定因素的全球图景仍然是一个巨大的挑战。我们分析了来自地球仪68个地点的243个塔拉Oceans样本的7.2个terabases宏基因组数据，以生成海洋微生物参考基因目录，其中包含来自病毒，原核生物和picoeukaryotes的> 4000万个非冗余，大部分是新序列。使用139个富含原核生物的样本，包含> 35，000个物种，我们显示了海洋上层群落组成的垂直分层，主要由温度而不是其他环境因素或地理因素驱动。我们确定了海洋微生物的核心功能，并揭示了尽管这两个生态系统之间存在物理化学差异，但其丰度的73%以上与人类肠道微生物组共享。
Microbes are dominant drivers of biogeochemical processes, yet drawing a global picture of functional diversity, microbial community structure, and their ecological determinants remains a grand challenge. We analyzed 7.2 terabases of metagenomic data from 243 Tara Oceans samples from 68 locations in epipelagic and mesopelagic waters across the globe to generate an ocean microbial reference gene catalog with >40 million nonredundant, mostly novel sequences from viruses, prokaryotes, and picoeukaryotes. Using 139 prokaryote-enriched samples, containing >35,000 species, we show vertical stratification with epipelagic community composition mostly driven by temperature rather than other environmental factors or geography. We identify ocean microbial core functionality and reveal that >73% of its abundance is shared with the human gut microbiome despite the physicochemical differences between these two ecosystems.