Risk factors for hospitalization in a cohort with type 1 diabetes. Wisconsin Diabetes Registry.
Risk factors for hospitalization in a cohort with type 1 diabetes. Wisconsin Diabetes Registry.
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1 型糖尿病队列中住院的危险因素。
DOI：
10.1093/oxfordjournals.aje.a009328
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发表时间：
1997
影响因子：
5
通讯作者：
D'Alessio,D
中科院分区：
文献类型：
--
作者：
Palta,M;LeCaire,T;Daniels,K;Shen,G;Allen,C;D'Alessio,D
作者调查了威斯康星州1987-1994年期间发病后住院率和危险因素，在一个基于人群的发病率队列中，从0-29岁诊断为1型糖尿病开始随访（n= 577）。糖尿病的总发生率为8.9 ± 0.60（标准误）/100人-年，其中5.7例是由于高血糖，1.9例是由于低血糖，1.3例是由于其他原因和未确定的原因。住院的主要危险因素是纵向测量的糖化血红蛋白水平（率比= 1.5/2%增加，95%置信区间1.4-1.7），黑人/其他人种（率比= 1.9，95%置信区间1.0-3.6），在非大学背景下诊断（率比= 1.9，95%置信区间1.2-3.2），女性（11岁时率比= 1.5，95%置信区间1.0-2.4），男性年龄（率比= 0.6，95%置信区间0.4-0.8每5年增加），和公共或无保险高达18个月诊断后（率比= 2.2，95%置信区间1.1-4.4）。对于18岁以下的个体，模型中的“黑人/其他种族”被“家中有两个以上的亲生父母”取代（率比= 2.0，95%置信区间1.1-3.5）。因此，住院治疗在儿童、青少年和青年糖尿病患者中很常见，主要是因为血糖控制问题。
The authors investigate the postonset hospitalization rate and risk factors during 1987–1994 in Wisconsin, in a population-based, incidence cohort followed from diagnosis of Type 1 diabetes mellitus at ages 0–29 (n= 577). The overall rate was 8.9 ± 0.60 (standard error) per 100 person-years of diabetes, whereof 5.7 was due to hyperglycemia, 1.9 to hypoglycemia, and 1.3 to other and undetermined causes. Major risk factors for hospitalization were longitudinally measured glycosylated hemoglobin level (rate ratio = 1.5 per 2% increase, 95% confidence interval 1.4–1.7), black/other race (rate ratio = 1.9, 95% confidence interval 1.0–3.6), diagnosis in a non-university-based setting (rate ratio = 1.9, 95% confidence interval 1.2–3.2), female sex (rate ratio = 1.5, 95% confidence interval 1.0–2.4 at age 11), age in males (rate ratio = 0.6, 95% confidence interval 0.4–0.8 per 5-year increase), and public or no insurance up to 18 months postdiagnosis (rate ratio = 2.2, 95% confidence interval 1.1–4.4). For individuals less than 18 years, “black/other race” was replaced in the model by “having other than two biologic parents in the home” (rate ratio = 2.0, 95% confidence interval 1.1–3.5). Hence, hospitalization is common in children, adolescents, and young adults with diabetes, primarily for problems with glycemic control.