Cotton Rats and House Sparrows as Hosts for North and South American Strains of Eastern Equine Encephalitis Virus
Cotton Rats and House Sparrows as Hosts for North and South American Strains of Eastern Equine Encephalitis Virus
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DOI：
10.3201/eid1609.100459
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发表时间：
2010-09-01
影响因子：
11.8
通讯作者：
Weaver, Scott C.
中科院分区：
文献类型：
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作者：
Arrigo, Nicole C.;Adams, A. Paige;Weaver, Scott C.
东部马脑炎病毒（EEEV;披膜病毒科，甲病毒属）是一种虫媒病毒，在北美的人类和整个美洲的马科动物中引起严重疾病。EEEV在北美的地方性传播周期涉及淡水沼泽栖息地的雀形目鸟类和嗜鸟蚊子媒介Culiseta melanura。然而，EEEV在南美洲的生态学还不清楚。黑锥库蚊蚊子被认为是中美洲和南美洲的主要媒介;然而，南美洲EEEV的主要脊椎动物宿主尚未被鉴定。因此，为了进一步评估野生啮齿类动物和野生鸟类的水库宿主潜力，我们比较了北美和南美EEEV在棉鼠（Sigmodon hispidus）和麻雀（Passer arteriticus）中的感染动态。我们的研究结果表明，每个物种都有潜力作为扩增主机的北美和南美EEEV。
Eastern equine encephalitis virus (EEEV; family Togaviridae, genus Alphavirus) is an arbovirus that causes severe disease in humans in North America and in equids throughout the Americas. The enzootic transmission cycle of EEEV in North America involves passerine birds and the ornithophilic mosquito vector, Culiseta melanura, in freshwater swamp habitats. However, the ecology of EEEV in South America is not well understood. Culex (Melanoconion) spp. mosquitoes are considered the principal vectors in Central and South America; however, a primary vertebrate host for EEEV in South America has not yet been identified. Therefore, to further assess the reservoir host potential of wild rodents and wild birds, we compared the infection dynamics of North American and South American EEEV in cotton rats (Sigmodon hispidus) and house sparrows (Passer domesticus). Our findings suggested that each species has the potential to serve as amplification hosts for North and South America EEEVs.