k-Space spatial low-pass filters can increase signal loss artifacts in echo-planar imaging
k-Space spatial low-pass filters can increase signal loss artifacts in echo-planar imaging
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DOI:
10.1016/j.bspc.2007.11.003
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发表时间:
2008-01-01
影响因子:
5.1
通讯作者:
Tomasi, D.
中科院分区:
文献类型:
--
作者:
Caparelli, E. C.;Tomasi, D.
Effective transverse relaxation rate (T(2)*)-weighted echo-planar imaging (EPI) is extensively used for functional magnetic resonance imaging (fMRI), because of its high speed and good sensitivity to the blood oxygenation level-dependent (BOLD) signal. Nevertheless. its use is limited in areas with severe static magnetic field inhomogeneities that cause frequency shifts and T(2)* relaxation-related distortions of the MR signal along the time-domain (k-space) trajectory, resulting in disperse fine-domain signals and generating susceptibility-induced signal losses. Echo planar images are commonly smoothed with k-space spatial low-pass filters to improve the signal-to-noise ratio (SNR) and reduce reconstruction artifacts. Here, we show that when such filters are applied to the dispersed echo-signals (not perfectly centered in k-space), part of the image information from the object is removed, thereby enhancing signal-loss artifacts in the images. To avoid this artifact, the dispersed echo signal has to be refocused before k-space filtering. (C) 2007 Elsevier Ltd. All rights reserved.