Silver nanocluster-based fluorescent sensors for sensitive detection of Cu(II)
Silver nanocluster-based fluorescent sensors for sensitive detection of Cu(II)
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用于灵敏检测 Cu(II) 的银纳米簇荧光传感器
DOI：
10.1039/b810409c
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发表时间：
2008-01-01
影响因子：
--
通讯作者：
Dong, Shaojun
中科院分区：
文献类型：
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作者：
Shang, Li;Dong, Shaojun
在这项工作中，我们首次报道了水溶性荧光银纳米团簇在荧光传感器中的应用。发现Cu2+对聚甲基丙烯酸(PMAA)模板银纳米团簇的荧光有较强的猝灭作用，但对其他常见金属离子的猝灭作用不明显。利用对分析物的特异性反应，建立了一种基于银纳米团簇的检测Cu2+的新的、简单、灵敏的荧光方法。在信噪比为3的条件下，该方法对Cu2+的检测范围为1×10−8M~6.0×10−6M，检测下限为8 nM。根据吸收光谱和荧光光谱的研究，讨论了Cu2+的猝灭机理，表明Cu2+通过与发射银纳米团簇周围的聚甲基丙烯酸甲酯聚合物的游离羧基结合而猝灭发射。此外，银纳米团簇对Cu2+的响应是可逆的，这进一步使本体系在传感器应用中具有吸引力。本研究表明，荧光金属纳米团簇的应用迈出了有希望的一步，这也可能为进一步设计和理解这些新材料奠定基础。
In this work, we report the first application of water-soluble fluorescent Ag nanoclusters in fluorescent sensors. The fluorescence of poly(methacrylic acid) (PMAA)-templated Ag nanoclusters was found to be quenched effectively by Cu2+, but not when other common metal ions were present. By virtue of the specific response toward the analyte, a new, simple, and sensitive fluorescent method for detecting Cu2+ has been developed based on Ag nanoclusters. The present assay allows for the sensing of Cu2+ in the range of 1.0 × 10−8 M to 6.0 × 10−6 M with a detection limit as low as 8 nM at a signal-to-noise ratio of 3. The quenching mechanism was discussed based on the absorption and fluorescence spectroscopy studies, which suggested that Cu2+ quenched the emission by binding with the free carboxylic groups of PMAA polymers that surround the emissive Ag nanoclusters. In addition, the response of Ag nanoclusters toward Cu2+ was found to be reversible, which further made the present system attractive for sensor applications. The present study shows a promising step toward the application of fluorescent metal nanoclusters, which may also serve as a foundation for the further design and understanding of these novel materials.