Sensory information processing during general anaesthesia: effect of isoflurane on auditory evoked neuronal oscillations.
Sensory information processing during general anaesthesia: effect of isoflurane on auditory evoked neuronal oscillations.
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全身麻醉期间的感觉信息处理：异氟烷对听觉诱发神经元振荡的影响。
DOI：
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发表时间：
1991
影响因子：
9.8
通讯作者：
Ernst Pöppel
中科院分区：
文献类型：
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作者：
C. Madler;I. Keller;D. Schwender;Ernst Pöppel
有证据表明，从神经心理学和心理物理学的测量，感觉信息是在离散的时间段处理。分割过程可以被描述为30-40 Hz频率的神经元振荡。在听觉诱发电位（AEP）的中间潜伏期范围内发现了该频率的刺激诱导的神经元振荡。本文研究了不同潮气末浓度异氟醚对听觉诱发的30-40 Hz神经元振荡的影响。我们研究了13例接受腹腔内泌尿外科和妇科手术的患者。在清醒状态和呼气末稳态异氟烷浓度为0.3、0.6和1.2体积%期间记录AEP。异氟烷的这些递增剂量导致振荡频率逐步降低。振荡频率的降低和有时振荡成分的消失可以解释为感觉信息处理的抑制。AEP中听觉诱发神经元振荡的测量似乎是监测感觉信息处理能力和麻醉深度的一种有前途的工具。
There is evidence from neuropsychological and psychophysical measurements that sensory information is processed in discrete time segments. The segmentation process may be described as neuronal oscillation at a frequency of 30-40 Hz. Stimulus-induced neuronal oscillations of this frequency are found in the middle latency range of the auditory evoked potential (AEP). We have studied the effect of different end-tidal concentrations of isoflurane on auditory evoked 30-40 Hz neuronal oscillations. We studied 13 patients undergoing intra-abdominal urological and gynaecological procedures. AEP were recorded in the awake state and during end-expiratory steady state isoflurane concentrations of 0.3, 0.6 and 1.2 vol%. These incremental doses of isoflurane caused a stepwise decrease in frequency of oscillations. The decrease in oscillation frequency and sometimes the disappearance of oscillatory components may be interpreted as suppression of sensory information processing. The measurement of auditory evoked neuronal oscillations in the AEP appears to be a promising tool to monitor both sensory information processing capacity and depth of anaesthesia.
DOI：
10.1016/0168-5597(86)90017-1
发表时间：
1986-09-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
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作者：
ERWIN, R;BUCHWALD, JS
通讯作者：
BUCHWALD, JS