Exercise training amount and intensity effects on metabolic syndrome (from studies of a targeted risk reduction intervention through defined exercise)
Exercise training amount and intensity effects on metabolic syndrome (from studies of a targeted risk reduction intervention through defined exercise)
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DOI：
10.1016/j.amjcard.2007.07.027
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发表时间：
2007-12-15
影响因子：
2.8
通讯作者：
Kraus, William E.
中科院分区：
文献类型：
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作者：
Johnson, Johanna L.;Slentz, Cris A.;Kraus, William E.
虽然运动可以改善代谢综合征（MS）的个体风险因素，但很少有关于运动对MS整体影响的研究。本研究的目的是确定建议进行多少运动以降低MS的患病率。在随机分配的334名受试者中，227名完成了运动，171名（80名女性，91名男性）具有所有5个成人治疗小组不明确的MS风险因素的完整数据，并被纳入本分析。受试者被随机分配到6个月对照组或3个8个月运动训练组中的1个：（1）低量/中等强度（相当于步行，类似于19 km/周），（2）低量/剧烈强度（相当于慢跑，类似于19 km/周），或（3）高量/剧烈强度（相当于慢跑，类似于32 km/周）。低量/中等强度运动处方相对于非活动对照改善了MS（p < 0.05）。然而，同样量的高强度运动并没有明显优于不活动的对照组，这表明低强度运动可能更有效地改善MS。相对于对照组，高强度/高强度运动组改善了MS（p < 0.0001）、低量/高强度组（p = 0.001）和中等强度组（p = 0.07），表明运动剂量效应。总之，在没有饮食变化的情况下，适量的中等强度运动显着改善了MS，因此支持成年人每天进行30分钟中等强度运动的建议。高强度的运动有更大和更广泛的好处。最后，有迹象表明，中等强度的运动可能比高强度的运动更能改善MS。（C）2007 Elsevier Inc. All rights reserved.
Although exercise improves individual risk factors for metabolic syndrome (MS), there is little research on the effect of exercise on MS as a whole. The objective of this study was to determine how much exercise is recommended to decrease the prevalence of MS. Of 334 subjects randomly assigned, 227 finished and 171 (80 women, 91 men) had complete data for all 5 Adult Treatment Panel Ill-defined MS risk factors and were included in this analysis. Subjects were randomly assigned to a 6-month control or 1 of 3 eight-month exercise training groups of (1) low amount/moderate intensity (equivalent to walking similar to 19 km/week), (2) low amount/vigorous intensity (equivalent to jogging similar to 19 km/week), or (3) high amount/vigorous intensity (equivalent to jogging similar to 32 km/week). The low-amount/ moderate-intensity exercise prescription improved MS relative to inactive controls (p < 0.05). However, the same amount of exercise at vigorous intensity was not significantly better than inactive controls, suggesting that lower-intensity exercise may be more effective in improving MS. The high-amount/vigorous-intensity group improved MS relative to controls (p < 0.0001), the low-amount/vigorous-intensity group (p = 0.001), and the moderate-intensity group (p = 0.07), suggesting an exercise-dose effect. In conclusion, a modest amount of moderate-intensity exercise in the absence of dietary changes significantly improved MS and thus supported the recommendation that adults get 30 minutes of moderate-intensity exercise every day. A higher amount of vigorous exercise had greater and more widespread benefits. Finally, there was an indication that moderate-intensity may be better than vigorous-intensity exercise for improving MS. (C) 2007 Elsevier Inc. All rights reserved.