Best Anthropometric and Atherogenic Predictors of Metabolic Syndrome in the Chinese Han Population in Xinjiang: The Cardiovascular Risk Survey
Best Anthropometric and Atherogenic Predictors of Metabolic Syndrome in the Chinese Han Population in Xinjiang: The Cardiovascular Risk Survey
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DOI：
10.1159/000366427
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发表时间：
2014-01-01
影响因子：
3.9
通讯作者：
Zheng, Ying-Ying
中科院分区：
文献类型：
--
作者：
Chen, Bang-Dang;He, Chun-Hui;Zheng, Ying-Ying
目的：本研究旨在通过比较新疆汉族人群各种人体测量和动脉粥样硬化参数的预测能力，确定代谢综合征（MetS）的最佳预测指标。方法：从2007年10月至2010年3月进行的心血管风险调查中选取5757名中国汉族成年人作为代表性的横断面样本。比较MetS的患病率、曲线下面积（AUC）、受试者工作特征曲线上的距离以及每个变量的截止值。结果：根据国际糖尿病联合会（IDF）、联合中期声明（JIS）和第三次成人治疗小组（ATPIII）的标准，新疆地区男性有32.1、48.5、39.3%的人患有met，女性有38.0、45.1、44.9%的人患有met。根据IDF标准，腰高比（WHtR）的AUC值男性最高（0.836），女性最高（0.837），最佳临界值男性为0.54，女性为0.53。根据JIS和ATPIII标准，甘油三酯/高密度脂蛋白胆固醇TG/HDL-C的AUC值在男性（分别为0.830和0.833）和女性（分别为0.832和0.827）中最高，最佳临界值在男性分别为1.6和1.2，女性分别为1.1和1.1。结论：根据IDF标准，WHtR是met的最佳预测指标，而根据JIS和ATPIII标准，TG/HDL-C是met的最佳预测指标。(C) 2014 S. Karger AG，巴塞尔
Objective: This study aimed to identify the best predictor of metabolic syndrome (MetS) by comparing the predicting ability of various anthropometric and atherogenic parameters in the Chinese Han population in Xinjiang. Methods: A representative, cross-sectional sample of 5,757 Chinese Han adults were selected from the Cardiovascular Risk Survey conducted from October 2007 to March 2010. MetS prevalence, area under the curve (AUC), distance on the receiver operating characteristic curve and the cut-offs of each variable were compared for the presence of MetS. Results: According to the criteria of the International Diabetes Federation (IDF), the Joint Interim Statement (JIS) and the Third Adult Treatment Panel (ATPIII), 32.1, 48.5, 39.3% of men and 38.0, 45.1, 44.9% of women had MetS in Xinjiang. According to the IDF criteria, the waist-to-height ratio (WHtR) had the highest AUC value in men (0.836) and women (0.837), with the optimal cut-off of 0.54 in men and 0.53 in women. According to both the JIS and ATPIII criteria, triglycerides/high-density lipoprotein cholesterol TG/HDL-C had the highest AUC value in men (0.830 and 0.833, respectively) and women (0.832 and 0.827, respectively), with the optimal cut-offs being 1.6 and 1.2 in men and 1.1 and 1.1 in women, respectively. Conclusion: WHtR was the best predictor of MetS according to the IDF criteria while TG/HDL-C was the best predictor of MetS according to the JIS and ATPIII criteria. (C) 2014 S. Karger AG, Basel