Influence of Enteral Nutrition on Occurrences of Necrotizing Enterocolitis in Very-Low-Birth-Weight Infants
Influence of Enteral Nutrition on Occurrences of Necrotizing Enterocolitis in Very-Low-Birth-Weight Infants
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DOI：
10.1097/mpg.0000000000000835
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发表时间：
2015-10-01
影响因子：
2.9
通讯作者：
Lima, Marilia de Carvalho
中科院分区：
文献类型：
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作者：
Kimak, Karine S.;de Castro Antunes, Margarida M.;Lima, Marilia de Carvalho
目的：本研究旨在探讨肠内喂养管理对极低出生体重儿坏死性小肠结肠炎（NEC）发生的影响。方法：这是一项病例对照研究，对2003年1月至2008年5月期间入住新生儿重症监护病房的1028名VLBW婴儿（750至1499 g）进行了样本研究。“病例”是指出生时患有VLBW并在出生后30天内被诊断为NEC的婴儿，而“对照组”是指在此期间未发生NEC的VLBW婴儿。使用改进的Bell标准定义NEC的发生（>= 2期）。结果：在1028例VLBW婴儿中，55例（5.4%）在出生后第一个月内发生NEC。Logistic回归分析显示，母乳只用于
Objective: The aim of the present study was to investigate the influence of enteral feeding management on occurrences of necrotizing enterocolitis (NEC) in very-low-birth-weight (VLBW) infants.Methods: This was a case-control study conducted in a sample of 1028 VLBW infants (750 to 1499 g) admitted to a neonatal intensive care unit between January 2003 and May 2008. "Cases" were infants born with VLBW and diagnosed with NEC within the first 30 days of life, and "controls" were VLBW infants who did not develop NEC during this period. Occurrences of NEC were defined using the modified Bell criteria (stage >= 2).Results: Among the 1028 VLBW infants, 55 (5.4%) developed NEC within the first month of life. Logistic regression analysis showed that breast milk given exclusively for