CORRELATION BETWEEN ARTICULAR-CARTILAGE COLLAGENASE ACTIVITY AND OSTEOARTHRITIS
CORRELATION BETWEEN ARTICULAR-CARTILAGE COLLAGENASE ACTIVITY AND OSTEOARTHRITIS
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DOI：
10.1002/art.1780210704
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发表时间：
1978-01-01
影响因子：
--
通讯作者：
MANKIN, HJ
中科院分区：
文献类型：
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作者：
EHRLICH, MG;HOULE, PA;MANKIN, HJ
从12个人股骨头获得的28个切片中测定关节软骨胶原酶活性。对于每1 cm 2区域，通过组织学-组织化学分级系统对切片进行关节炎严重程度分级。胶原酶活性主要在中度严重疾病的区域发现，但在轻度或终末期关节炎中没有发现。
Articular cartilage collagenase activity was determined for 28 sections obtained from 12 human femoral heads. For each 1 cm2 area, a section was graded by a histologic-histochemical grading system for the severity of the arthritis. Collagenase activity was found primarily in those areas of moderately severe disease, but not in mild or end stage arthritis.