Gradient of fatty acids from blood plasma to skeletal muscle in dogs.
Gradient of fatty acids from blood plasma to skeletal muscle in dogs.
复制标题
狗的脂肪酸从血浆到骨骼肌的梯度。
DOI：
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发表时间：
1995
影响因子：
3.3
通讯作者：
T. Roemen
中科院分区：
文献类型：
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作者：
G. J. van der Vusse;T. Roemen
在麻醉犬中，测定了动脉血和股二头肌的脂肪酸、三酰甘油和磷脂组分中脂肪酰基部分的量，以描述从血液到骨骼肌组织的脂肪酸梯度（如有）的存在。发现股二头肌中的脂肪酸含量非常低（约占组织样品中未酯化和酯化脂肪酰基部分总量的0.1%）。动脉血浆中脂肪酸含量（nmol/ml）与脂肪酸组织水平（nmol/g湿重）的比值约为17。这一发现支持了这样的观点，即从血管隔室到骨骼肌纤维的脂肪酸梯度可能是骨骼肌净提取脂肪酸的驱动力之一。
In anesthetized dogs, the amount of fatty acyl moieties in the fatty acid, triacylglycerol, and phospholipid fractions of arterial blood and biceps femoris muscle has been determined to delineate the presence of a fatty acid gradient from blood to skeletal muscle tissue, if any. The content of fatty acids in biceps femoris muscle was found to be very low (approximately 0.1% of total amount of unesterified and esterified fatty acyl moieties in the tissue sample). The ratio of the content of fatty acids (nmol/ml) in arterial plasma and the tissue level of fatty acids (nmol/g wet weight) was approximately 17. This finding supports the notion that a fatty acid gradient from the vascular compartment to the skeletal muscle fibers might be one of the driving forces of net extraction of fatty acids by skeletal muscle.