Measurement of ultrasmall volumes using anodic stripping voltammetry.
Measurement of ultrasmall volumes using anodic stripping voltammetry.
复制标题
使用阳极溶出伏安法测量超小体积。
DOI：
10.1021/ac011036s
复制
发表时间：
2002
影响因子：
7.4
通讯作者：
Fritsch,Ingrid
中科院分区：
文献类型：
--
作者：
Vandaveer4th,WalterR;Fritsch,Ingrid
本文讨论了一种新的、有效的小体积测定方法。小体积工作的好处很多，包括使用更少的材料，产生更少的废物，在更小的空间内增加功能，便携性和高吞吐量。随着样本量的减少，测量其体积变得更具挑战性。小体积测定最常用的方法是目视检查。本文提出的方法是精确的，更定量的，并适应于许多解决方案的几何形状，因为它是基于库仑法。该方法的演示是在含有银的100 nL体积上进行的，并使用含有多个电极的自含式微腔装置。银在阴极电位步骤期间“耗尽”沉积，随后进行阳极溶出伏安法。预计使用这种方法可以更快、更准确地分析比此处评估的体积小得多的体积。
This paper discusses a new and effective method for small volume determination. The benefits of working with small volumes are numerous and include using less material, generating less waste, increased functionality in less space, portability, and high throughput. As sample size decreases, measuring its volume becomes more challenging. The most prevalent method for small volume determination is visual inspection. The method presented in this paper is precise, more quantitative, and adaptive to many solution geometries, because it is based on a coulometric approach. Demonstration of this method is performed on volumes of ∼1 nL containing silver and using a self-contained microcavity device that contains multiple electrodes. The silver is “exhaustively” deposited during a cathodic potential step, followed by anodic stripping voltammetry. It is expected that an even faster and more accurate analysis of volumes much smaller than those evaluated here is easily possible using this approach.