A new anthraquinone from Morinda citrifolia roots
A new anthraquinone from Morinda citrifolia roots
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DOI：
10.1080/14786410902753138
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发表时间：
2009-01-01
影响因子：
2.2
通讯作者：
Lee, H. L.
中科院分区：
文献类型：
--
作者：
Ee, G. C. L.;Wen, Y. P.;Lee, H. L.
从海巴戟天的根中分离得到一个新的蒽醌类化合物2-乙氧基-1-羟基蒽醌（1），沿着分离得到5个已知的蒽醌类化合物：1-羟基-2-甲基蒽醌（2），damnacanthal（3），去甲damnacanthal（4），2-甲酰基-1-羟基蒽醌（5）和morindone-6-甲基-醚（6）。本文首次报道从该植物中分离得到桑茚酮-6-甲醚（6）。通过NMR、MS和IR等波谱分析，确定了化合物的结构，并对5个化合物及其提取物进行了杀埃及伊蚊活性评价，结果表明1-羟基-2-甲基蒽醌（2）和虎刺醛（3）是具有较好杀蚊活性的提取物。
An investigation of Morinda citrifolia roots afforded a new anthraquinone, 2-ethoxy-1-hydroxyanthraquinone (1), along with five other known anthraquinones: 1-hydroxy-2-methylanthraquinone (2), damnacanthal (3), nordamnacanthal (4), 2-formyl-1-hydroxyanthraquinone (5) and morindone-6-methyl-ether (6). This is the first report on the isolation of morindone-6-methyl-ether (6) from this plant. The structures of these compounds were elucidated based on spectroscopic analyses such as NMR, MS and IR. Biological evaluation of five pure compounds and all the extracts against the larvae of Aedes aegypti indicated 1-hydroxy-2-methylanthraquinone (2) and damnacanthal (3) were the extracts to exhibit promising larvicidal activities.