Diagnostic value of three-dimensional fluid-attenuated inversion recovery MR imaging after intratympanic administration of contrast media in Meniere's disease
Diagnostic value of three-dimensional fluid-attenuated inversion recovery MR imaging after intratympanic administration of contrast media in Meniere's disease
复制标题
三维流体衰减反转恢复磁共振成像鼓室内注射造影剂对梅尼埃病的诊断价值
DOI：
10.3760/cma.j.issn.1005-1201.2012.10.003
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Xiaoni Man
中科院分区：
文献类型：
--
作者：
Honglu Shi;Guangbin Wang;X. Bai;Li;Xiaoni Man
目的通过鼓膜注入钆后，三维液体衰减反转恢复磁共振成像（MRI）方法经鼓膜注入钆后24 h，行3D-FLAIR磁共振成像，观察内淋巴显影情况及对梅尼埃病的诊断价值。对19例临床诊断为单侧梅尼埃病的患者在3.0T磁共振机上进行3D-FLAIR和3D-Balance-FFE成像，观察前庭和（或）耳道，分别对双侧耳蜗底回的鼓阶和前庭阶进行评分，测量双侧前庭强化范围及前庭与脑干的信号强度比（SIR）。结果在3D-FLAIR图像上，耳蜗、前庭和（或）耳道内淋巴液几乎全部可见钆离子，内淋巴间隙清晰可见，患侧前庭阶评分与患侧前庭阶评分比较，差异有统计学意义（P < 0. 05）。2分3例，1分9例，0分7例（15例评分为2分，2例评分为1分，2例评分为0分）有显著差异（U = 3.090，P < 0.05），前庭增强区的面积（5.77 ± 2.33）mm 2，患侧与健侧平均直径为（8.11 ± 3.32）mm 2，差异有显著性U = 3.090，P < 0.05和t = 2.638，P < 0.05）。结论根据3D-Balance-FFE MRI和外淋巴间隙强化，三维-通过鼓膜鼓室内注射钆的FLAIR MRI可用于显示外淋巴和内淋巴之间的边界，证实内淋巴积水，从而为梅尼埃病的诊断提供影像学依据。
关键词：
梅尼埃病;内淋巴积水;磁共振成像
Objective After intratympanic gadolinium administration through the tympanic membrane,three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) was performed to evaluate endolymphatic visualization and its diagnostic value in Meniere's disease.Methods Twenty-four hours after intratympanic gadolinium administration through the tympanic membrane,19 patients with unilateral Meniere's disease diagnosed clinically underwent 3D-FLAIR and 3D-Balance-FFE imaging at 3.0 T MR scanner.The enhanced imaging of perilymphatic space in bilateral cochlea,vestibular and (or) canal were observed.Scala tympani and scala vestibule of bilateral cochlear basal turn were scored respectively.The enhanced range of bilateral vestibule and the signal intensity ratio (SIR) between the vestibule and the brain stem were measured. Wilcoxon tests and paired t tests were used.Results The gadolinium appeared in almost all parts of the perilymph in cochlea,vestibular and (or) canal,so the endolymphatic space was clearly visualized on 3D-FLAIR imaging.The score of scala vestibuli between the affected side (3 cases scored 2,9 cases scored 1,7 cascs scored 0) and the healthy side ( 15 cases scored 2,2 cases scored 1,2 cases scored 0 ) were significantly different ( U =3.090,P ＜ 0.05 ).The area of enhanced vestibular were (5.77 ± 2.33) mm2 and (8.11 ± 3.32) mm2 for the affected side and the healthy side,which were significantly different ( U =3.090,P ＜ 0.05 and t =2.638,P ＜ 0.05 ).Conclusions According to 3D-Balance-FFE MRI and the enhancement of perilymphatic space,3D-FLAIR MRI with intratympanic gadolinium injection through the tympanic membrance can be used to show the border between the perilymph and the endolymph and confirm endolymphatic hydrops,thus providing radiographic evidence for the diagnosis of Meniere's disease.
Key words:
Meniere's disease; Endolymphatic hydrops; Magnetic resonance imaging