Association of maternal prepregnancy weight and early childhood weight with obesity in adolescence: A population‐based longitudinal cohort study in Japan
Association of maternal prepregnancy weight and early childhood weight with obesity in adolescence: A population‐based longitudinal cohort study in Japan
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母亲孕前体重和儿童早期体重与青春期肥胖的关联：日本基于人群的纵向队列研究
DOI：
10.1111/ijpo.12597
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发表时间：
2020
影响因子：
3.8
通讯作者：
Kawakami Koji
中科院分区：
文献类型：
--
作者：
Yoshida Satomi;Kimura Takeshi;Noda Masahiro;Takeuchi Masato;Kawakami Koji
背景出生体重和儿童早期肥胖对青春期肥胖的影响尚不清楚。目的探讨15岁超重/肥胖与出生体重、儿童早期超重/肥胖和母亲超重/肥胖的关系。方法：这项以人群为基础的回顾性队列研究使用了1581名日本儿童的幼儿和学龄健康检查数据，随访至15岁。采用广义估计方程分析探讨15岁超重/肥胖与低/高出生体重、3岁超重/肥胖和母亲超重/肥胖的关系。所有变量的截止点均按国际标准确定。结果1581对母婴中，低出生体重儿童130例（8.2%），3岁和15岁时超重/肥胖儿童分别为93例（5.9%）和167例（10.6%）。3岁时超重/肥胖和母亲超重/肥胖与15岁时超重/肥胖相关(调整优势比[aOR]， 4.26； 95%可信区间[CI]: 2.51-7.25和（aOR, 2.46; 95% CI: 1.41-4.30）。低出生体重和15岁时超重/肥胖之间没有关联。结论母亲超重/肥胖和3岁时超重/肥胖与15岁时超重/肥胖相关，但与出生体重无关。
BackgroundThe impact of birth weight and obesity in early childhood on obesity in adolescence remains unclear.ObjectivesTo examine the association of overweight/obesity at age 15 years with birth weight, overweight/obesity in early childhood and overweight/obesity in mothers.MethodsThis population‐based retrospective cohort study used early childhood and school age health check‐up data of 1581 children in Japan, followed‐up until age 15 years. Generalized estimation equation analyses were used to investigate the association of overweight/obesity at age 15 years with low/high birth weight, overweight/obesity in 3 years of age and overweight/obesity in mothers. The cutoff points for all variables were defined by international criteria.ResultsOf 1581 mother‐child pairs, 130 (8.2%) children had low birth weight, while 93 (5.9%) and 167 (10.6%) were overweight/obese at age 3 and 15 years, respectively. Overweight/obesity at age 3 years and overweight/obesity in mothers were associated with overweight/obesity at age 15 years (adjusted odds ratio [aOR], 4.26; 95% confidence interval [CI]: 2.51–7.25 and (aOR, 2.46; 95% CI: 1.41–4.30). No association between low birth weight and overweight/obesity at age 15 years was observed.ConclusionsOverweight/obesity in mothers and overweight/obesity at 3 years of age, but not birth weight, were associated with overweight/obesity at age 15 years.