Recruiting vulnerable populations to participate in HIV prevention research: findings from the Together 5000 cohort study

Recruiting vulnerable populations to participate in HIV prevention research: findings from the Together 5000 cohort study
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DOI:
10.1016/j.annepidem.2019.05.003
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发表时间:
2019-07-01
影响因子:
5.6
通讯作者:
Nash, Denis
Nash, Denis
中科院分区:
医学3区
文献类型:
--
作者:
Grov, Christian;Westmoreland, Drew A.;Nash, Denis

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目的:本文的目的是在5000名与男性发生性行为的高危男性(n=8661)、变性人(n=53)和变性女性(n=63)队列中,检查与完成登记里程碑相关的因素。方法:2017至2018年间,参与者完成了一项在线登记调查,并获得了完成激励性二级在线调查和自我管理的家庭艾滋病毒检测(OraSure)的机会。结果:共有8777人完成了注册调查,6166人(70.3%)完成了二次调查,5010人退回了寄给他们的HIV检测试剂盒(81.3%)。在我们的多变量模型中,那些受教育年限较长的白人更有可能完成学习部分,尽管这些联系的规模很小。例如,50.9%的登记受试者、47.9%完成二次调查的受试者和46.8%完成HIV检测的受试者是有色人种,这在统计上是显著的,但意义不大。结论:这些发现突显了研究人员需要找出可能阻止有色人种和年轻人参与研究的障碍。(C)2019 Elsevier Inc.保留所有权利。
Purpose: The aim of the article was to examine factors associated with completing enrollment milestones in the Together 5000 cohort of at-risk men (n = 8661), transmen (n = 53), and transwomen (n = 63) who have sex with men.Methods: Between 2017 and 2018, participants completed an online enrollment survey and were offered opportunities to complete an incentivized secondary online survey as well as self-administered at-home HIV testing (OraSure). We explored factors associated with completing each study component.Results: In total, 8777 individuals completed our enrollment survey, 6166 (70.3%) completed the secondary survey, and 5010 returned the at-home HIV test kit that was mailed to them (81.3% of those mailed a kit). In our multivariable models, those who were White, with more years of education, were more likely to complete study components, although the magnitude of these associations was small. For example, 50.9% of those enrolled, 47.9% of those completing the secondary survey, and 46.8% of those completing HIV testing were persons of color a statistically significant, but meaningfully insignificant decline.Conclusions: These findings highlight the need for researchers to identify barriers that may prevent persons of color and younger individuals from participating in research studies. (C) 2019 Elsevier Inc. All rights reserved.