Arsenic in drinking water and pregnancy outcomes
Arsenic in drinking water and pregnancy outcomes
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DOI：
10.2307/3455038
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发表时间：
2001-06-01
影响因子：
10.4
通讯作者：
Talukder, HK
中科院分区：
文献类型：
--
作者：
Ahmad, SA;Sayed, SU;Talukder, HK
我们研究了一组通过饮用水长期接触砷的育龄妇女(15-49岁)，以确定活产、死产、自然流产和早产的妊娠结局。我们比较了接触砷污染水的受试者和未接触砷污染水的育龄妇女(15-49岁)的妊娠结局。在一项横断面研究中，我们将暴露组和非暴露组的女性在年龄、社会经济地位、教育程度和结婚年龄方面进行了匹配。总样本量为192人，每组有96名妇女(即暴露和不暴露)。接触组中98%的人饮用砷含量大于或等于0.1 mg/L的水，43.8%的人饮用砷污染水5~10年。22.9%的受访者有慢性砷暴露所致的皮肤症状。在自然流产、死产和早产率方面，接触组的不良妊娠结局显著高于非接触组(分别为p=0.008、p=0.046和p=0.018)。
We studied a group of women of reproductive age (15-49 years) who were chronically exposed to arsenic through drinking water to identify the pregnancy outcomes in terms of live birth, stillbirth, spontaneous abortion, and preterm birth. We compared pregnancy outcomes of exposed respondents with pregnancy outcomes of women of reproductive age (15-49 years) who were not exposed to arsenic-contaminated water. In a cross-sectional study, we matched the women in both exposed and nonexposed groups for age, socioeconomic status, education, and age at marriage. The total sample size was 192, with 96 women in each group (i.e., exposed and nonexposed). Of the respondents in the exposed group, 98% had been drinking water containing greater than or equal to 0.10 mg/L arsenic and 43.8% had been drinking arsenic-contaminated water for 5-10 years. Skin manifestation due to chronic arsenic exposure was present in 22.9% of the respondents. Adverse pregnancy outcomes in terms of spontaneous abortion, stillbirth, and preterm birth rates were significantly higher in the exposed group than those in the nonexposed group (p = 0.008, p = 0.046, and p = 0.018, respectively).