Change in incidence rates for psychosis in different ethnic groups in south London: findings from the Clinical Record Interactive Search-First Episode Psychosis (CRIS-FEP) study.
Change in incidence rates for psychosis in different ethnic groups in south London: findings from the Clinical Record Interactive Search-First Episode Psychosis (CRIS-FEP) study.
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DOI：
10.1017/s0033291719003234
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发表时间：
2021-01
影响因子：
6.9
通讯作者：
Morgan C
中科院分区：
文献类型：
--
作者：
Oduola S;Das-Munshi J;Bourque F;Gayer-Anderson C;Tsang J;Murray RM;Craig TKJ;Morgan C
在黑人和其他少数民族群体中，特别是在北欧，精神病障碍的发病率一直较高。目前还不清楚这些利率是否随着时间的推移而发生了变化。我们确定了所有在2010年5月1日至2012年4月30日期间到成人精神卫生服务机构就诊并居住在伦敦兰贝斯区和南沃克区的首发精神病患者。我们估计了总体和种族群体的年龄和性别标准化发病率，然后将我们的发现与大约10年前我们在同一地区进行的精神分裂症和其他精神病的病因学和种族(？SOP)研究中报告的结果进行了比较。从9109份临床记录中，我们确定了558名首发精神病患者。与？SOP相比，伦敦东南部精神障碍的总发病率从每10万人年49.4(95%可信区间43.6-55.3)增加到63.1(95%可信区间57.3-69.0)。然而，一些族裔群体的总发病率比率(IRR)有所下降：例如，加勒比黑人群体的IRR(95%CI)从6.7(5.4-8.3)下降到2.8(2.1-3.6)，“混合”群体从2.7(1.8-4.2)下降到1.4(0.9-2.1)。在非洲黑人组中，差异可以忽略不计，从4.1(3.2-5.3)到3.5(2.8-4.5)。我们发现，精神病的发病率随着时间的推移而增加，而且IRR因种族而异。未来的研究需要调查随着时间的推移发生的更多变化以及变化的决定因素。
A higher incidence of psychotic disorders has been consistently reported among black and other minority ethnic groups, particularly in northern Europe. It is unclear whether these rates have changed over time. We identified all individuals with a first episode psychosis who presented to adult mental health services between 1 May 2010 and 30 April 2012 and who were resident in London boroughs of Lambeth and Southwark. We estimated age-and-gender standardised incidence rates overall and by ethnic group, then compared our findings to those reported in the Aetiology and Ethnicity of Schizophrenia and Other Psychoses (ÆSOP) study that we carried out in the same catchment area around 10 years earlier. From 9109 clinical records we identified 558 patients with first episode psychosis. Compared with ÆSOP, the overall incidence rates of psychotic disorder in southeast London have increased from 49.4 (95% confidence interval (CI) 43.6–55.3) to 63.1 (95% CI 57.3–69.0) per 100 000 person-years at risk. However, the overall incidence rate ratios (IRR) were reduced in some ethnic groups: for example, IRR (95% CI) for the black Caribbean group reduced from 6.7 (5.4–8.3) to 2.8 (2.1–3.6) and the ‘mixed’ group from 2.7 (1.8–4.2) to 1.4 (0.9–2.1). In the black African group, there was a negligible difference from 4.1 (3.2–5.3) to 3.5 (2.8–4.5). We found that incidence rates of psychosis have increased over time, and the IRR varied by the ethnic group. Future studies are needed to investigate more changes over time and determinants of change.