IONESCU-SHILEY PERICARDIAL XENOGRAFTS - FOLLOW-UP OF UP TO 6 YEARS
IONESCU-SHILEY PERICARDIAL XENOGRAFTS - FOLLOW-UP OF UP TO 6 YEARS
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DOI：
10.1016/s0003-4975(10)62547-7
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发表时间：
1985-01-01
影响因子：
4.6
通讯作者：
KEON, WJ
中科院分区：
文献类型：
--
作者：
BRAIS, MP;BEDARD, JP;KEON, WJ
使用Ionescu-Shiley心包异种移植物进行瓣膜置换的结果优于使用其他生物瓣膜获得的结果。从1977年3月到1983年7月，在加拿大渥太华大学心脏研究所的463名患者中植入了497个Ionescu-Shiley心包瓣膜。主动脉瓣置换术（AVR）292例，二尖瓣置换术（MVR）140例，双瓣置换术28例，三瓣置换术3例。幸存者被定期跟踪。晚期结果的精算分析表明，接受AVR的患者6年时的预期生存率为71%，接受MVR的患者3年时的预期生存率为72%。唯一的瓣膜相关死亡是由于心内膜炎，二尖瓣的发生率为3.9%/患者-年。尽管正规抗凝治疗的使用率较低，但主动脉瓣栓塞并发症的发生率为1.4%/患者-年，二尖瓣为4.0%/患者-年。5个瓣膜在36-72个月后因内在失效而被移除。的后续行动。纽约心脏协会心功能分级平均改善1.28级/例。
The results of valve replacement with the Ionescu-Shiley pericardial xenograft compare favorably with results obtained with other bioprostheses. from March 1977 to July 1983, 497 Ionescu-Shiley pericardial valves were implanted in 463 patients at the University of Ottawa Heart Institute [Canada]. There were 292 patients who had aortic valve replacement (AVR), 140 with mitral valve replacement (MVR), 28 with double valve replacement and 3 with triple valve replacement. The survivors were followed regularly. Actuarial analysis of late results indicated an expected survival of 71% at 6 yr for patients who underwent AVR and 72% at 3 yr for patients who had MVR. The only valve-related deaths were due to endocarditis, which occurred at a rate of 3.9%/patient-yr for mitral valves. Despite a low usage of formal anticoagulation, embolic complications occurred at a rate of 1.4%/patient-yr for aortic valves and 4.0%/patient-yr for mitral valves. Five valves were removed for intrinsic failure after 36-72 mo. of follow-up. New York Heart Association Functional Class improved an average of 1.28 classes/patient.